Choroidal Tuberculoma Manifesting in A Patient of Eales Disease 6 Years after Initial Presentation

Magesan, Kowsigan; Majumder, Parthopratim Dutta

doi:10.1080/09273948.2018.1536792

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Ocular tuberculosis can be associated with Eales disease and often manifest later in the course of the disease. 9 Our patient presented with small choroidal granulomas of unknown aetiology in OS in the course of treatment which responded well to oral corticosteroids. ATT was not added in our patient due to absence of any definitive evidence of intraocular or extraocular tuberculosis.…”

Section: Discussionmentioning

confidence: 70%

A Case of Recurrent Vasculitic Vitreous Haemorrhage in One Eye and Idiopathic Choroidal Granulomas in The Fellow Eye of A Young Individual

Aggarwal¹,

Nishant²,

Sood³

et al. 2021

DJO

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A 26-year-old male presented with sudden diminution of vision in right eye (OD) for 15 days. Best-corrected visual acuity (BCVA) was finger counting 1-metre in OD and 6/6 in left eye (OS). Fundus examination revealed fresh vitreous haemorrhage (VH) in OD. Investigations including complete haemogram, VDRL, Mantoux test and Contrast-Enhanced Computed Tomography chest were normal. A presumptive diagnosis of Eales disease was made. Subsequently he also developed multiple small choroidal granulomas in OS. He was started on oral corticosteroid and treated with multiple episodes of scatter-laser and intravitreal bevacizumab in OD for recurrent VH. He ultimately required parsplana vitrectomy in OD for persistent VH despite anti-VEGF and laser. Choroidal granulomas in OS disappeared after treatment with oral steroid. He maintained BCVA of 6/6 in both eyes after 6-months and was kept under close followup. Multimodal approach and combination modality of treatment may be required for optimal outcome in such cases.

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Section: Discussionmentioning

confidence: 70%

A Case of Recurrent Vasculitic Vitreous Haemorrhage in One Eye and Idiopathic Choroidal Granulomas in The Fellow Eye of A Young Individual

Aggarwal¹,

Nishant²,

Sood³

et al. 2021

DJO

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“…Although no difference was found in the humoral and cell mediated immune response to mycobacterial A60 antigen, ED has a shared human leucocyte antigen predisposition (HLAB51, DR4) similar to Behçet's disease and VKH disease 13 , 14 . Natural course of this entity can change over time as a previously immunocompetent tuberculin negative ED subject with occlusive vasculitis developed tuberculoma six years after initial presentation 84 .…”

Section: Clinical Spectrum Of Ocular Inflammation Associated With Bcgmentioning

confidence: 99%

Bacille Calmette-Guérin: An ophthalmic perspective

Jain

Vadboncoeur

Biswas

2022

Survey of Ophthalmology

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Vaccines such as bacille Calmette-Guérin (BCG) are known for their heterologous effects mediated through a number of mechanisms, including trained immunity constituted by monocyte-macrophage based innate immunity. Other events such as direct hematogenous spread and induction of autoimmunity are also described. There has been a resurgent interest in harnessing some of the benefits of trained immunity in the management of COVID-19, even as several specific vaccines have been approved. We summarize the current knowledge of ocular effects of BCG. Potential effect of granulomatous inflammation on angiotensin converting enzyme activity and accentuation of cytokine storm that may result in undesirable ocular and systemic effects are also discussed.

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Choroidal Tuberculoma Manifesting in A Patient of Eales Disease 6 Years after Initial Presentation

Cited by 2 publications

References 8 publications

A Case of Recurrent Vasculitic Vitreous Haemorrhage in One Eye and Idiopathic Choroidal Granulomas in The Fellow Eye of A Young Individual

A Case of Recurrent Vasculitic Vitreous Haemorrhage in One Eye and Idiopathic Choroidal Granulomas in The Fellow Eye of A Young Individual

Bacille Calmette-Guérin: An ophthalmic perspective

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