Choroidal thickness profile in normal Iranian eyes with different refractive status by spectral-domain optical coherence tomography

Heirani, Mohsen; Shandiz, Javad Heravian; Shojaei, Ahmad; Narooie-Noori, Foroozan

doi:10.1016/j.joco.2019.08.005

Cited by 14 publications

(16 citation statements)

References 77 publications

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“…In a cohort study in China, patients with myopia had a lower CT compared with emmetropic patients, and patients with high myopia had the lowest CT values (14). In another study, Heirani et al (15) examined CT and refractive status and found that patients with myopia had a lower CT and patients with hyperopia had a greater CT. Similarly, we also found that myopic patients had a lower CT and hyperopic patients had a greater CT.…”

Section: Discussionmentioning

confidence: 99%

Comparison of retinal and choroidal structures among three refractive groups

Aydemir¹

2021

Beyoglu Eye J

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Objectives: This study investigated the retinal layer thickness, choroidal thickness (CT), and retinal nerve fiber layer (RNFL) parameters in 3 refractive groups. Methods: A total of 201 eyes of 201 subjects were enrolled in this prospective and comparative study. The patients were divided into 3 groups according to refractive status: Group 1 consisted of 60 eyes of myopic subjects, Group 2 comprised 72 eyes of emmetropic subjects, and 69 eyes of hyperopic subjects were categorized as Group 3. The retinal layer thickness, CT, and RNFL parameters were measured using optical coherence tomography and compared between groups. Results:The mean age of the patients was 22.33±10.11 years in Group 1, 21.55±8.3 years in Group 2, and 23.73±11.08 years in Group 3 (p=0.741). Group 1 consisted of 34 women and 26 men, Group 2 contained 44 women and 28 men, and Group 3 was made up of 45 women and 24 men (p=0.124). The mean spherical equivalent value was −6.16±2.01 D in Group 1, 0.13±0.5 D in Group 2, and 5.48±1.32 D in Group 3 (p<0.001). The RNFL and macular thickness values were lower in the myopic patients compared with those of the other groups (p<0.05). The CT measurement was lower in the myopic patients and higher in the hyperopic patients compared with the emmetropic patients (p<0.05). Conclusion:The myopic patients had a lower CT and RNFL thickness measurement than the emmetropic and hyperopic patients, whereas the hyperopic patients had a higher CT than the other patient types.

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Section: Discussionmentioning

confidence: 99%

Comparison of retinal and choroidal structures among three refractive groups

Aydemir¹

2021

Beyoglu Eye J

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“…Choroidal thickness measurements vary among different studies, as this can be affected by factors such as patient’s ethnicity, age, refractive error, and axial length, the light source used in the OCT device, and software used to measure [ 13 , 14 ]. Although it has been shown that the Iranian population has a thicker choroid ranging from 329 to 363 μm compared to some other ethnicities [ 13 , 14 ]. The current study showed that patients with FIPED had a higher choroidal thickness compared to the fellow eye and also normal eyes.…”

Section: Discussionmentioning

confidence: 99%

Choroidal features in flat irregular pigment epithelial detachment associated with Chronic central serous chorioretinopathy: Avascular versus vascularized

et al. 2021

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Purpose To investigate the differences in the choroidal biomarkers between two forms of flat irregular pigment epithelial detachment (FIPED): avascular (aFIPED) and vascularized (vFIPED) in eyes with chronic central serous chorioretinopathy (CSC). Materials and methods Enhanced depth imaging optical coherence tomography (EDI-OCT) was done in eyes with FIPED correlated to chronic CSC, fellow eyes, and also in healthy eyes from gender- and age-matched subjects. Eyes with FIPED were classified into two subgroups based on optical coherence tomography angiography (OCTA) findings: vFIPED and aFIPED. Different choroidal biomarkers such as subfoveal choroidal thickness (SFCT), total choroidal area (TCA), and choroidal vascular index (CVI) were compared between the groups. Results Forty-four eyes from 42 patients with chronic CSC and FIPED along with 40 eyes from 20 healthy subjects were included. OCTA identified vascularization in 14 eyes in the FIPED group (31.8%). Mean SFCT was higher in the FIPED group compared to two other groups (p = 0.005). In comparison to patients with aFIPED, patients with vFIPED had lower SFCT (p = 0.003) and higher CVI (p = 0.020) based on multivariate analysis. Conclusions It seems that measurement of CVI along with SFCT may help to differentiate aFIPED from vFIPED in patients with CSC. Further longitudinal studies would be required to confirm the clinical significance of these findings.

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“…They also showed that the subfoveal CT was similar to that in the superior temporal quadrant, however, it was greater than that in the inferior nasal quadrant. Heirani et al ( 44 ) demonstrated that the choroid was thickest at 1 mm superior to the fovea and thinnest at 3 mm nasal to the fovea. Recently, using SS-OCT system with a 12 × 12-mm 3D volume scan centered on the fovea, Breher et al ( 45 ) showed that CT gradually decreased with an increasing distance from the fovea.…”

Section: Choroidal Thickness Measurement At the Maculamentioning

confidence: 99%

Choroidal Thickness Profile in Chorioretinal Diseases: Beyond the Macula

Kim

2021

Front. Med.

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Enhanced depth imaging optical coherence tomography (EDI-OCT) and swept-source OCT (SS-OCT) have emerged as essential diagnostic tools in the study and management of various chorioretinal diseases. Evidence from early clinical studies using EDI-OCT and SS-OCT indicates that choroidal dysfunction plays a major role in the pathogenesis of chorioretinal diseases. Measurement of choroidal thickness (CT) has already become a major research and clinical method, and CT is considered as an indicator of choroidal status in a variety of ophthalmic diseases. Recently, CT measurement has also been proposed as a non-invasive marker for the early detection and monitoring of various systemic diseases. Among the several possible CT measurement locations, subfoveal CT has rapidly become a reliable parameter for measuring CT in healthy and diseased eyes. Moreover, recent advancements in OCT technology have enabled faster and wider imaging of the posterior part of the eye, allowing the various changes in CT as measured outside the macula to be shown accordingly. In this review, we first provide an overview of the results of clinical studies that have analyzed the healthy macular choroid and that in various chorioretinal diseases, and then summarize the current understanding of the choroid outside the macula. We also examine the CT profile as an index that encompasses both within and outside of the macula. Furthermore, we describe the clinical applications of ultrawide OCT, which enables visualization of the far periphery, and discuss the prospects for the development of more reliable choroidal parameters that can better reflect the choroid's characteristics.

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Choroidal thickness profile in normal Iranian eyes with different refractive status by spectral-domain optical coherence tomography

Cited by 14 publications

References 77 publications

Comparison of retinal and choroidal structures among three refractive groups

Comparison of retinal and choroidal structures among three refractive groups

Choroidal features in flat irregular pigment epithelial detachment associated with Chronic central serous chorioretinopathy: Avascular versus vascularized

Choroidal Thickness Profile in Chorioretinal Diseases: Beyond the Macula

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