Choroidal neovascularization treated with intravitreal injection of bevacizumab (Avastin) in angioid streaks

Intravitreal bevacizumab for choroidal neovascularisation secondary to causes other than age-related macular degeneration

“…45 All reports indicate an improvement of vision in the short term (Table 3). [46][47][48][49][50][51][52][53][54] The longest followup is approximately 2 years (range: 3-24 months). There are several interesting trends among studies of angioid-streak-related CNV treatment with antiangiogenic agents.…”

Intravitreal bevacizumab for treatment of choroidal neovascularization secondary to angioid streaks

“…2,3 Although, there is one reported case of treatment of CNV, secondary to angioid streaks with intravitreal bevacizumab, we have not been able to find additional cases in the English literature. 4 We believe that this case illustrates the need for a randomized trial in order to evaluate the efficacy of intravitreal bevacizumab or other anti-vascular endothelial growth factor Sir, Bilateral congenital hamartomas of the retinal pigment epithelium in a patient with Down's syndrome Congenital hamartoma of the retinal pigment epithelium (RPE) was first described by Laqua 1 in 1981, based on the clinical observation in two cases. Since then, not more than 20 unilateral cases of RPE hamartomas have been reported in the literature.…”

Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks

“…It has been generally agreed that following PDT treatment the greatest linear CNV diameter, which indicates lesion size, is increased at the time of final examination when compared to initial lesion diameter (5) , indicating disease progression despite PDT. Anti-VEGF treatment of CNV due to angioid streaks was first reported by Teixeira et al, (9) who reported increased BCVA and decreased disease activity following bevacizumab injection. In addition, in 2007 Lommatzsch et al reported a single case of CNV due to angioid streaks (10) .…”