Choroid Plexus Papilloma with Chondroma: Case Report

Salazar, J; Vaquero, Jesús; Aranda, Ignacio; Menéndez, J. L.; Jimenez, Dolores; Bravo, G.

doi:10.1227/00006123-198606000-00018

Cited by 37 publications

(17 citation statements)

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“…Surgical removal is the treatment of choice, as complete removal with careful resection of all dural attachments can result in an excellent long-term outcome (19,20). .…”

Section: Discussionmentioning

confidence: 99%

Characteristic CT and MRI Findings of Intracranial Chondroma

et al. 2012

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“…Surgical removal is the treatment of choice, as complete removal with careful resection of all dural attachments can result in an excellent long-term outcome (19,20). .…”

Section: Discussionmentioning

confidence: 99%

Characteristic CT and MRI Findings of Intracranial Chondroma

et al. 2012

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“…They may exhibit a wide spectrum of histologic patterns, including acinar (3,4), mucussecreting (5,6), oncocytic (7,8), pigmented (9,10), tubular (11), and metaplastic (5,12,13) variants. Distinguishing these tumors from metastatic carcinomas, a matter of considerable therapeutic and prognostic significance, therefore can be problematic.…”

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confidence: 99%

Cytokeratin 7 and 20 Expression in Choroid Plexus Tumors: Utility in Differentiating These Neoplasms from Metastatic Carcinomas

Gyure

Morrison

2000

Modern Pathology

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Choroid plexus tumors are relatively rare lesions, accounting for fewer than 1% of intracranial neoplasms (1, 2). They may exhibit a wide spectrum of histologic patterns, including acinar (3, 4), mucussecreting (5, 6), oncocytic (7,8), pigmented (9, 10), tubular (11), and metaplastic (5, 12, 13) variants. Distinguishing these tumors from metastatic carcinomas, a matter of considerable therapeutic and prognostic significance, therefore can be problematic. A number of potential immunohistochemical markers for choroid plexus tumors, including glial fibrillary acidic protein (14 -25), S-100 protein (14 -17, 21, 23), vimentin (14 -17), cytokeratin (CK) (14 -20, 22), non-CK epithelial markers (16, 17, 21, 26), carcinoembryonic antigen (14, 15, 18, 21), neuronal markers (15, 21, 27), and transthyretin (14, 21, 23, 28, 29), have been evaluated; however, their utility has been limited by a lack of specificity and by the conflicting results yielded by these studies. Recently, the evaluation of the coordinate expression of CK7 and CK20 has been shown to be of use in distinguishing primary from metastatic lesions in a number of anatomic sites (30 -32). The CK7/CK20 immunophenotypes of a large number of neoplasms have been characterized (Table 1). Moreover, it has been shown that these lesions retain their CK7/CK20 immunophenotype in metastatic locations, including the brain (33).We examined 35 choroid plexus tumors with a panel of antibodies, including CK7 and CK20, to determine their immunophenotype. The potential diagnostic implications of these findings are discussed.

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“… 10 Salazar et al. 11 reported an example of CPP coexisting with chondroma, which is probably a related entity. All of these cases followed a benign clinical course, and there are no examples of malignant transformation (or progression) of bone‐ or cartilage‐forming CPP.…”

Section: Discussionmentioning

confidence: 99%

Ossifying choroid plexus papilloma recurring with features of atypical papilloma

Shintaku¹,

Nitta

Matsubayashi

et al. 2008

Neuropathology

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A case of ossifying choroid plexus papilloma (CPP) with an unusual clinical course is reported. The patient was a 46-year-old woman who underwent surgery for a 3-cm tumor occupying the fourth ventricle. The tumor showed typical histopathological features of CPP, and the formation of psammoma bodies and mature bone trabeculae was prominent in the stroma. The tumor recurred locally after a dormant period of 15 years, and the recurrent lesion showed invasion of the cerebellum as well as increased cellularity, cellular stratification, nuclear atypism, and mitotic activity, all of which were consistent with a diagnosis of "atypical" CPP. The recurrent tumor did not show ossification of the stroma, although many psammoma bodies were found. There have been very few reported cases of ossifying CPP, and all of the previous cases behaved in a benign fashion. The present case is the first report of ossifying CPP that showed postoperative recurrence with progression to atypical CPP after an unusually long dormant period.

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Choroid Plexus Papilloma with Chondroma: Case Report

Cited by 37 publications

References 0 publications

Characteristic CT and MRI Findings of Intracranial Chondroma

Characteristic CT and MRI Findings of Intracranial Chondroma

Cytokeratin 7 and 20 Expression in Choroid Plexus Tumors: Utility in Differentiating These Neoplasms from Metastatic Carcinomas

Ossifying choroid plexus papilloma recurring with features of atypical papilloma

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