Choroid Plexus Metastasis of Lung Carcinoma

Abstract

Metastatic tumors in the choroid plexus are generally considered to be very rare. The authors present a case of lung large cell carcinoma with a single metastatic tumor in the choroid plexus of the lateral ven tricle trigone. Precontrast computed tomographic (CT) scans showed an isodensity mass with exten sive peritumoral edema, which was considerably enhanced on the postcontrast CT scans. Magnetic resonance (MR) images demonstrated the mass as a low-intensity area on the T,-weighted image and an iso-intensity area on the T<SUB>2</SUB>-weighted image. The tumor was clearly differentiated from the peritu moral edema by both CT and MR imaging. The diagnosis was confirmed by surgery.

Solitary metastasis to the choroid plexus of the lateral ventricle

“…In our Case 2, the increased density on plain CT and good enhancement were compatible with the features of meningioma, except for marked brain edema [19]. Tanimoto et al [8] stressed that extensive edema surrounding metastatic tumors in the choroid plexus of the lateral ventricle was characteristic, and the most important feature for differentiating metastasis from meningioma. In all our cases, extensive peritumoral edema was recognized on T2 weighted image, and therefore, metastatic tumor should be included in the differential diagnosis of an intraventricular tumor with marked peritumoral edema.…”

“…According to the Japan Brain Tumor Registry [1], there were 37 cases of metastases to the lateral ventricle (0.9%) among 3917 cases of brain metastasis. In the literature, we found 18 reported cases of metastatic tumor to the choroid plexus of the cerebral ventricles [4][5][6][7][8][9][10][11]14]; among these cases, eight involved a single metastasis to the choroid plexus of the lateral ventricle [4][5][6][7][8][9][10][11]. The primary cancers in the eight reported cases and the three present ones were renal cell carcinoma in four cases, lung cancer in three, and other kinds of cancer in four (including one patient of unknown primary site) ( Table 1).…”

“…A postoperative physical survey revealed a tumor in the left lung, which was later diagnosed as primary adenocarcinoma. Table 1 summarizes the clinical features of single brain metastasis to the choroid plexus of the lateral ventricle from the eight cases reported previously [4][5][6][7][8][9][10][11] and the present three cases. The ages of the 11 patients (including one patient of unknown age) ranged from 29 to 78 years (mean 59.0 years) with a male predominance (male:female = 9:1).…”

“…Only eight cases of single metastatic tumor to the choroid plexus of the lateral ventricle have been reported in the literature [4][5][6][7][8][9][10][11]. In this paper, we report our experience with three cases of single brain metastasis growing in the choroid plexus of the lateral ventricle, and discuss the differential diagnosis from other tumors with reference to previously reported cases.…”

Choroid Plexus Metastasis of Colon Cancer

“…Only seventeen histologically conˆrmed cases have been reported (Table). [2][3][4][5][6][7][8][9][10][11][12][13] The ages of the reported cases ranged from 45 to 78 years with a mean age of 62.8 years. All metastatic lesions were located in the lateral ventricle except for only two cases located in the fourth ventricle.…”