Choroid plexus metastases from pleural sarcomatoid mesothelioma

Muljono, Anita; Ng, Tsz Wai; McMaster, Jacqueline; Dexter, Mark

doi:10.1080/00313020802198051

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…In our review of the literature, we identified less than 20 cases of patients with symptomatic metastatic mesothelioma. The previous cases with neurosurgical management are grouped in the Table [2][3][4][5] . It was previously believed that mesothelioma was a process limited mostly to the thoracic cavity but, in recent autopsy case series, it was found that up to 50% of patients with mesothelioma had some type of distant metastases.…”

Section: Discussionmentioning

confidence: 99%

Neurosurgical Management of Intracranial Metastatic Mesothelioma

Westwick¹,

Jansen²,

Silva³

2013

Can. J. Neurol. Sci.

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Mesothelioma is a relatively rare tumor arising from the pleura, most notably associated with exposure to asbestos 1 . Typically, mesothelioma is a locally aggressive tumor with a poor outcome in the order of months from the time of diagnosis 2 . Although cases of distant metastases of mesothelioma have been documented in the literature, this tumor has less reported cases of metastases than other malignancies of the chest, and most reported cases of metastases have been identified in autopsy studies, likely related to the short survival times of patients harboring these tumors.Brain metastases of mesothelioma are particularly uncommon, with approximately 100 cases documented 3 . Most commonly brain metastases have been discovered in autopsy studies of patients with mesothelioma, but in a small percentage of cases, the diagnosis was made before death. Neurosurgical Management of Intracranial Metastatic MesotheliomaHarrison J. Westwick, Gerard H. Jansen, Vasco F. Da Silva Can J Neurol Sci. 2013; 40: 878-880 BRIEF COMMUNICATIONSWe have identified only seven reported cases in the literature where neurosurgical intervention was undertaken to manage symptomatic intracranial metastases of mesothelioma, with previous cases tabulated by Winfree and colleagues 3 . Only three previous cases reported surgical intervention for metastatic mesothelioma in the posterior fossa 3,4 . In these seven reported cases, only one was found to have a post-resection survival time of more than three months.We present this case because of its rarity in neurosurgical pathology. Intracranial metastatic mesothelioma must be entertained as a possible site of tumor metastases in the case of a patient with known mesothelioma. We also report this case to indicate the role of neurosurgical management in the management of a symptomatic patient with intracranial metastatic mesothelioma.

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Section: Discussionmentioning

confidence: 99%