Choroid Plexus Free-Water Correlates with Glymphatic function in Alzheimer Disease: The RJNB-D Study
Binyin Li,
Xiaomeng Xu,
Xinyuan Yang
et al.
Abstract:The free water imaging of choroid plexus (CP) may improve the evaluation of Alzheimer's disease (AD). Our study investigated the role of free water fraction (FWf) of CP in AD by including 216 participants (133 Aβ + participants and 83 Aβ- controls) continuously enrolled in the NeuroBank-Dementia cohort at Ruijin Hospital (RJNB-D). At baseline, Aβ + participants showed higher CP free water fraction (FWf), increased white matter hyperintensity (WMH) volume, and decreased diffusion tensor image analysis of the pe… Show more
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