Chorioangiom der Plazenta – eine seltene Ursache fetaler High-Output-Herzinsuffizienz

Abstract

ZusammenfassungPlazentare Chorangiome sind als benigne Tumore des Choriongewebes seltene Ursache fetaler und maternaler Morbidität. Wir beschreiben den Fall eines großen plazentaren Chorangioms, das zu einem Polyhydramnion, konsekutiver Frühgeburt und kindlicher High-Output-Herzinsuffizienz führte. Aus einer Literaturrecherche leiten wir zudem Hinweise zur Diagnostik und Empfehlungen zur optimalen Schwangerschaftsbetreuung bei Verdacht auf Chorioangiom ab.

Giant Placental Chorangioma and Severe Ductal Arch Constriction: A Case Report With a Favorable Outcome

“…These tumors act as arteriovenous shunts that increase fetal cardiac output. Additionally, fetal blood sequestration within the tumor’s vascular array may cause microangiopathic hemolytic anemia [ 10 ]. Together, these mechanisms underlie the onset of common non-structural anomalies such as FGR, high-output heart failure, fetal anemia, fetal hydrops, and polyhydramnios [ 11 ].…”

Mixed chorangioma of the placental disk of a 29-year-old pregnant woman: A case report with literature review

“…The main clinical correlation in the pathology of Chorangioma is its association with pregnancy 2-4 outcomes. While the majority of Chorangiomas are small and clinically insignificant, larger lesions (> 4 cm) have been associated with adverse 2,3,6,7,9,12,13,15,22,24 pregnancy outcomes.…”

“…These large Chorangiomas may be associated with perinatal morbidity and even mortality due to hemodynamic stresses on the 3,7,9,12,13,15 fetus.…”

“…Complications such as intrauterine growth restriction (IUGR), fetal anemia, arteriovenous shunting, fetal cardiomegaly, fetal heart failure, fetal thrombocytopenia, and fetal 3,4,7,[11][12][13]15,22 hydrops have been reported.…”