2019
DOI: 10.1212/con.0000000000000763
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Chorea

Abstract: PURPOSE OF REVIEW This article provides an overview of the approach to chorea in clinical practice, beginning with a discussion of the phenomenologic features of chorea and how to differentiate it from other movement disorders. The diagnostic approach, clinical features of important acquired and genetic choreas, and therapeutic principles are also discussed. Practical clinical points and caveats are included. RECENT FINDINGS C9orf72 disease is the most … Show more

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Cited by 27 publications
(37 citation statements)
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“…Chorea is a hyperkinetic movement disorder described as random, flowing, and dancelike [ 1 ]. In many conditions chorea is generalized, involving the entire body, however, in a significant number of situations, the movement disorder can be strikingly asymmetric or even unilateral.…”
Section: Introductionmentioning
confidence: 99%
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“…Chorea is a hyperkinetic movement disorder described as random, flowing, and dancelike [ 1 ]. In many conditions chorea is generalized, involving the entire body, however, in a significant number of situations, the movement disorder can be strikingly asymmetric or even unilateral.…”
Section: Introductionmentioning
confidence: 99%
“…While unilateral involvement is classically related to a contralateral structural lesion, e.g. of the putamen or the subthalamic nucleus, with stroke as the most common etiology, systemic disease can also lead to a unilateral or markedly asymmetric presentations [ 1 ]. In particular, hyperglycemic hemichorea/hemiballismus is typically described as being unilateral with transient T1 hyper intensity of the contralateral putamen on magnetic resonance imaging [ 2 3 4 5 ].…”
Section: Introductionmentioning
confidence: 99%
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“…Neuropathy, myopathy, cardiomyopathy, seizures, and parkinsonism may also occur. 1 Core subsets of neuroacanthocytosis include the autosomal recessive chorea-acanthocytosis (ChAc) caused by mutations in the VPS113A gene and the X-linked Mcleod syndrome (MLS) caused by mutations in the XK gene encoding the Kell antigen on erythrocytes. ChAc has a mean age of onset of 35 years and tends to be associated with severe feeding dystonia and subsequent weight loss, difficulties with saccades, a "rubber man" posture and gait, and atrophy of the caudate nucleus.…”
Section: Discussionmentioning
confidence: 99%
“…The term choreoathetosis is used when typical choreic movements coexist with athetosis. It seems that the basal ganglia are the main structures involved in its pathophysiology [24,25].…”
Section: Choreoathetosismentioning
confidence: 99%