Chordomas of the upper cervical spine: radiographic evaluation. Study of two cases and review of the literature

Kokkinis, K.; Vlychou, Marianna; Stathopoulou, Sotiria; Λαζούρα, Όλγα; Makris, Nikos; Evangelopoulos, Dimitrios-Stergios; Benetos, Ioannis S.; Papadaki, Paraskevi J.; Korres, Demetrios S.

doi:10.1007/s00590-007-0250-0

Cited by 1 publication

(1 citation statement)

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“…In addition, authors have described that chordoma subtype influenced recurrence rates with de-differentiated, conventional chordoma, then chondroid chordoma having the worst prognosis in descending order. [ 14 ] Of all recurrent chordomas, there were 42 patients with unspecified chordoma type, 29 patients had conventional chordoma, one patient had dedifferentiated chordoma, and one patient had giant cell chordoma.…”

Section: Discussionmentioning

confidence: 99%

Outcomes following surgical management of cervical chordoma: A review of published case reports and case series

Pham

Awad

2017

Asian J Neurosurg

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Aim:This review aimed to summarize the clinical outcomes in relation to tumor resection margins of cervical chordomas.Methods:Studies that described any surgical intervention for cervical chordoma were identified. Cervical chordomas with cranial or spinal extension, purely retropharyngeal chordomas or where resection type was not reported, were excluded from the study.Results:Seventy-six articles were obtained and these reported a total of 195 patients. Seventy-six percent cervical chordoma patients had intralesional resection with adjuvant radiotherapy. Ninety-two percent chordoma recurrences and all chordoma metastases occurred in patients with intralesional resection. En bloc surgeries were longer (900 min vs. 619 min) and staged surgeries. Intralesional surgeries (2899 ml vs. 2661 ml) had greater intraoperative blood loss. Vertebral artery and nerve root sacrifice were greater in en bloc patients (35%, 39%) compared to intralesional patients (17%, 10%). Postoperative complications were more common in en bloc (54%) than in intralesional patients (11%).Conclusions:En bloc resection cervical chordomas are associated with less recurrence and no metastasis compared to intralesional resection. En bloc is possible through wide exposure of the vertebrae via a multidisciplinary team approach and utilization of particular surgical equipment. The higher rate of complications associated with en bloc surgeries may be acceptable, particularly when there is a chance of cure of disease.

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Section: Discussionmentioning

confidence: 99%