Chordoma: Ultrastructural, Biochemical and Cytophotometric Findings

Mikuz, Gregor; Mydla, F.; Gütter, W.

doi:10.1016/s0005-8165(77)80094-2

Cited by 23 publications

(2 citation statements)

References 9 publications

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“…Biochemical investigations do not indicate a difference between the acid mucopolysaccharides in the tumor and in the nucleus pulposus, but the stor,age capacity of individual cells does seem to lie enhanced. 24 Cytophotometri.c investigations indicate that Only the are The The malignant potential of a chordoma lies in its origin in critical anatomical sites, a locally aggressive behavior, and an extremely high recurrence rate. Metastases from craniocervical chordomas are are.^.^^ Complete surgical removal offers the best chance for cure but is rarely, if ever, achieved in the craniocervical region.…”

Section: Chordomamentioning

confidence: 99%

The pathology of head and neck tumors: Neoplasms of cartilage, bone, and the notochord, part 7

1980

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Neoplasms of the supporting tissues in the head and neck are outnumbered by their histologic counterparts in the trunk and extremities. This is especially true for tumors of bone, cartilage, and the remnants of the notochord. Malignancies occurring in all three tissues, however, are just as lethal as those sited elsewhere. Chondrosarcomas and osteogenic sarcomas of the facial bones are resistant to all conventional modes of therapy, manifest many recurrences, and have an often protracted morbidity. The craniocervical chordoma manifests a similar biologic course. For the tumors of cartilaginous origin and the osteogenic sarcomas, the initial surgical attempt at removal is of key importance. Neoplasms present at the margins of resection have a poor prognosis. Chorodomas are not likely to be cured by any modality.

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Section: Chordomamentioning

confidence: 99%

The pathology of head and neck tumors: Neoplasms of cartilage, bone, and the notochord, part 7

1980

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“…At first the cells contain large amounts of glycogen, but this diminishes as the cells ripen and at the same time the vacuoles appear. The intercellular matrix is usually rich in mucin (Byers, 1981 ;Eriksson et al, 1981;Mikuz et al, 1977;Thiery et al, 1977).…”

Section: Discussionmentioning

confidence: 99%

Chondroid chordoma of the base of the skull: Orbital and other neuro-ophthalmological symptoms

et al. 1983

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Key words: chordoma of the base of the skull, chondroid chordoma, orbital ap_ex syndrome due to chordoma, ophthalmoplegia dolorosa due to chordoma Abstract. Chondroid chordoma of the base of the skull has a significantly more favourable prognosis than the classical chordoma. The clinical and radiological symptoms of this relatively benign form, and its histological and therapeutic aspects, are discussed in connection with the case of a 50-year-old patient.

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Electron Microscopy in Bone Tumor Diagnosis

Roessner¹,

Grundmann²

1982

Current Topics in Pathology

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Chordoma: Ultrastructural, Biochemical and Cytophotometric Findings

Cited by 23 publications

References 9 publications

The pathology of head and neck tumors: Neoplasms of cartilage, bone, and the notochord, part 7

The pathology of head and neck tumors: Neoplasms of cartilage, bone, and the notochord, part 7

Chondroid chordoma of the base of the skull: Orbital and other neuro-ophthalmological symptoms

Electron Microscopy in Bone Tumor Diagnosis

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