Chordoma: results of radiation therapy in eighteen patients

Romero, Jesús; Cárdenes, Higinia R.; Torre, Antonio La; Valcárcel, Francisco; Magallón, Rosa; Regueiro, C.A.; Aragón, G.

doi:10.1016/0167-8140(93)90169-9

Cited by 107 publications

(33 citation statements)

References 25 publications

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“…Romero et al 22 reported eight patients with clivus chordomas treated with conventional RT for gross tumor at the Puerta de Hierro Hospital (Madrid, Spain) between 1975 and 1990, with a follow-up of at least 1 year. Four patients died with tumor at 33, 41, 42, and 52 months, respectively.…”

Section: Resultsmentioning

confidence: 98%

Skull base chordoma

Mendenhall¹,

Mendenhall²,

Lewis³

et al. 2005

Head Neck

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Section: Resultsmentioning

confidence: 98%

Skull base chordoma

Mendenhall¹,

Mendenhall²,

Lewis³

et al. 2005

Head Neck

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“…Historical series of photon rt demonstrated 5-year local control rates in the 20% range 34,35 , which improved in small series of stereotactic 36 and image-guided rt 37 (published only in abstract form) to 50% and 77% respectively for skull base chordoma and to 100% and 93% respectively for skull base chondrosarcomas. A review of 621 patients treated with combined proton-photon rt at the Harvard Cyclotron Laboratory reported 5-year local relapse-free and overall survival rates of 73% and 80% respectively for skull base chordoma and 98% and 91% respectively for skull base chondrosarcomas 38 .…”

Section: Chordoma and Chondrosarcomamentioning

confidence: 99%

Recommendations for the Referral of Patients for Proton-Beam Therapy, an Alberta Health Services Report: A Model for Canada?

et al. 2014

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able and willing to travel abroad to a proton facility. Commonly accepted indications for referral include chordoma and chondrosarcoma, intraocular melanoma, and solid tumours in children and adolescents who have the greatest risk for long-term sequelae. Current data do not provide sufficient evidence to recommend routine referral of patients with most head-and-neck, breast, lung, gastrointestinal tract, and pelvic cancers, including prostate cancer. It is recommended that all referrals be considered by a multidisciplinary team to select appropriate cases.

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“…Various working groups have been able to achieve LC rates of 46-74% at 5 years for chordoma [21][22][23][24][25] (Table 2) and of 78-98% for chondrosarcoma (Table 3) with the use of particle radiation. As these tumours are rare, however, pooled data are very often published for chordoma and chondrosarcoma.…”

Section: Base Of Skull Tumours: Chordoma and Chondrosarcomamentioning

confidence: 99%

Review of clinical experience with ion beam radiotherapy

Jensen

Münter²,

Debus³

2011

BJR

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ABSTRACT. The article describes both the early development of oncology as a core discipline at the University of Heidelberg Hospital and the first steps towards ion beam treatment, from the pilot project carried out in co-operation with the Gesellschaft fü r Schwerionenforschung Darmstadt to the initial start-up of clinical service at the Heidelberg Heavy Ion Centre (HIT). We present an overview, based on data published in the literature, of the available clinical evidence relating the use of ion beam therapy to treat major indications in active particle centres. A rationale for the use of particle therapy in each of these indications is given. In view of the limited availability of data, we discuss the necessity to conduct clinical trials. We also look forward towards the next activities to be undertaken at the HIT.

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Chordoma: results of radiation therapy in eighteen patients

Cited by 107 publications

References 25 publications

Skull base chordoma

Skull base chordoma

Recommendations for the Referral of Patients for Proton-Beam Therapy, an Alberta Health Services Report: A Model for Canada?

Review of clinical experience with ion beam radiotherapy

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