“…There are many symptoms and signs potentially associated with ARS, including sneezing, malaise, fever, cough, nasal discharge, nasal obstruction, cough, sore throat and headache, however many of these are nonspecific and can also be seen in isolated nasal infection or inflammation as well as with allergy flares 299,301,303,307–309 . The 3 cardinal symptoms and signs that otolaryngology, rhinology, and infectious disease experts have agreed upon to diagnose ARS are: up to 4 weeks of purulent nasal drainage, accompanied by nasal obstruction, or facial pain/pressure/fullness, or both 26,31,88,146,310 . These cardinal symptoms and signs do not have high level of evidence backing them up but instead have been agreed upon multiple times over many years by various task forces and consensus groups.…”