Chondrosarcoma of the Posterior Mediastinum

Webster, B. H.

doi:10.1378/chest.31.1.104

Cited by 3 publications

(4 citation statements)

References 6 publications

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“…Actually, less than ten cases of mediastinal chondrosarcoma have been reported (2,7) . Moreover, this malignancy is particularly unusual in the posterior mediastinum (3) . There is a slight male predominance in most series, with a median age near 50 years (2) .…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, chondrosarcoma in any part of the mediastinum is exceedingly rare. It is particularly unusual in the posterior mediastinum (3) . The posterior mediastinum is the potential space along each side of the vertebral column and adjacent proximal portion of the ribs.…”

Section: Introductionmentioning

confidence: 99%

“…Neurogenic tumors are considered the commonest posterior mediastinal tumors are accounting for 19%-39% of all mediastinal tumors and 75% of all posterior mediastinal tumors (4) .They are presented by schwannomas which account for about 90% of all dumbbell tumors. Rarely, dumbbell mass is made by chondrosarcoma (3,5) . In some cases, based only on clinical and radiologic features, posterior mediastinal chondrosarcoma could be misdiagnosed as a nerve sheath tumor (3) .…”

Section: Introductionmentioning

confidence: 99%

“…Rarely, dumbbell mass is made by chondrosarcoma (3,5) . In some cases, based only on clinical and radiologic features, posterior mediastinal chondrosarcoma could be misdiagnosed as a nerve sheath tumor (3) . Such a case that we report.…”

Section: Introductionmentioning

confidence: 99%

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Posterior Mediastinal Chondrosarcoma Presenting as a Dumbbell-shaped Mass Mimicking a Cystic Schwannoma: An Unusual Presentation

Kouadir

Mazghi²,

Hassouni³

et al. 2017

IAM

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Mediastinal chondrosarcoma is exceedingly rare. Moreover, it is particularly unusual in the posterior mediastinum. Actually, very few cases of chondrosarcoma of the posterior mediastinum are gleaned from the literature. On the other hand, neurogenic tumors make even more than 75% of all tumors in the posterior mediastinum, and they are most often schwannomas that account for about 90% of all dumbbell-shaped tumors. Exceptionally, a dumbbell-shaped mass may correspond to a chondrosarcoma. We report a case of a 48-year-old Moroccan woman who presented with a complaint of intermittent electric shock type pain in the right side of chest radiating to the ipsilateral arm over six months period. No apparent distress or mass was found during the physical examination. Chest X-ray showed wellcircumscribed opacity located in the upper right part of the posterior mediastinum. Neck and chest computed tomography (CT) scans followed by magnetic resonance imaging (MRI) were carried out and revealed a dumbbellshaped mass of the posterior mediastinum. Such radiologic findings have oriented towards the diagnosis of cystic schwannoma. As pathologic results were inconclusive after a CT-guided fine needle biopsy, the patient underwent tumor resection via right posterolateral thoracotomy. Histopathological examination of surgical resection specimen revealed a grade II chondrosarcoma with the invasion of peripheral margins. Therefore, the patient received adjuvant radiation therapy to the tumor bed. Our case suggests that in the case of a dumbbell-shaped or thoracic paravertebral tumor a diagnosis other than nerve sheath tumor should be considered, including chondrosarcoma.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Posterior Mediastinal Chondrosarcoma Presenting as a Dumbbell-shaped Mass Mimicking a Cystic Schwannoma: An Unusual Presentation

Kouadir

Mazghi²,

Hassouni³

et al. 2017

IAM

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Extraskeletal Cartilaginous Tumors

Uehara¹,

Becker²

1960

AMA Arch Surg

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Primary mediastinal chondrosarcomas: do they really exist?

Zaleski¹,

Truong²,

Moran³

2020

Mediastinum

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Chondrosarcomas primarily originating in the mediastinal compartment are vanishingly rare. Contrary to other unusual tumors of the mediastinum, chondrosarcomas have been described in either anterior or posterior mediastinum. The histopathological spectrum that has been described in these mediastinal tumors is similar to that described in soft tissues. In our current practice, diagnostic imaging plays an important role before any of these neoplasms is rendered as of mediastinal origin. It is also important to highlight that even though a tumor may be presenting as a mediastinal tumor, such information in essence does not constitute that the tumor is not in fact associated with another structure within the thoracic cavity, thus the importance of strict radiological correlation. Furthermore, molecular characterization of tumors that in the past were coded under the spectrum of chondrosarcomas, are now believed to represent different tumoral conditions, which raises important issues in tumor classification. Therefore, in this review, we will outline a more specific criteria regarding the diagnosis of chondrosarcomas, as wells as the essentials in the histopathological assessment of these tumors. In addition, we will discuss the current knowledge of these entities as well as their differential diagnosis, which inevitably will depend on the anatomic distribution of the tumor—anterior or posterior compartment.

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Chondrosarcoma of the Posterior Mediastinum

Cited by 3 publications

References 6 publications

Posterior Mediastinal Chondrosarcoma Presenting as a Dumbbell-shaped Mass Mimicking a Cystic Schwannoma: An Unusual Presentation

Posterior Mediastinal Chondrosarcoma Presenting as a Dumbbell-shaped Mass Mimicking a Cystic Schwannoma: An Unusual Presentation

Extraskeletal Cartilaginous Tumors

Primary mediastinal chondrosarcomas: do they really exist?

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