Chondrosarcoma of the hyoid bone

Abstract

Chondrosarcoma of the head and neck is relatively rare. We report the sixth case known to us in which the chondrosarcoma had originated in the hyoid bone. The patient, a 66-year-old man, underwent surgery. The resected tumour was a 5 cm encapsulated lesion composed of lobulated, firm, gray-white tissue. Histologically it showed mature chondrocytes without capsular invasion. There was high cellularity and a few binucleated chondrocytes. Although the tumour grade was prognostic significance, our literature review of the five other cases suggests that the location of the primary lesion and the adequacy of its resection to be more important. Our patient continues to do well 15 months post-operatively. However, long-term follow-up is essential as recurrences have been reported even after eight or 10 years.

A low-grade chondrosarcoma presenting as an unusual cervical mass in the hyoid bone: a case report

“…Signal intensity is low in T1-weighted images and high in T2-weighted images; the calcified portion is signal-free. A characteristic finding is a mosaic pattern in high signal areas in T2-weighted images [4]. In our case, a CT examination demonstrated no evidence of bone destruction, but revealed intratumoral calcification.…”

Chondrosarcoma of the hyoid bone: Case report and review of current management options

“…CT is helpful in demonstrating characteristic calcifications and cortical breakthrough, but MRI is the primary type of diagnostic imaging. Chondrosarcomas classically appear hypointense with peripheral enhancement on T1‐weighted MRI and hyperintense on T2‐weighted imaging . MRI is more sensitive to the lobulations and enhancing septations in low‐grade chondrosarcomas and the diffuse heterogenous enhancement in highly aggressive tumors; however, these characteristics are not necessary for the diagnosis .…”

“…Adequacy of surgical resection seems to be the most important factor for preventing local and distant recurrence of chondrosarcomas . These tumors tend to recur after any incomplete excision . Figure shows that 83% of patients with no recurrence had negative surgical margins; conversely, 100% of patients with recurrence had nonnegative (positive or unreported) margins.…”

“…We conducted a detailed search of the published medical literature before September 2012 in MEDLINE and PubMed using the terms “chondrosarcoma” and “hyoid.” The search led to 19 case reports of the tumor (Table ) . We retrospectively reviewed these patients' data, including presenting symptoms, management, and outcome.…”

Mucin-secreting papillary adenocarcinoma of the hyoid bone: a unique case

“…Primary tumours of the hyoid previously described in the literature have included chondrosarcomas 12 and giant cell tumours. 13 The hyoid has never been proven as a primary source of squamous carcinoma 10 but bony metastases of head and neck squamous cell carcinomas have been reported as infiltrating the hyoid in 1.6 per cent of laryngeal specimens with pathological evidence of squamous cell carcinoma.…”