Chondromyxoid fibroma of the parietal bone

Abstract

We report the case of an 11-year old girl who presented with an intracranial chondromyxoid fibroma arising from parietal bone. Chondromyxoid fibroma is a benign cartilaginous neoplasm, which can be easily mistaken for chondrosarcoma, especially in small biopsies. It is more common in long bones and is least common in cranial bones. Published work describes about 33 cases occurring in cranial bones with almost equal incidence in the bones of the base of the skull and cranial vault. To our knowledge, this is the second case of chondromyxoid fibroma reported to occur in parietal bone and is the first case reported in an English-language journal. We present this case for its rare anatomical, clinical, radiological and histological presentations.

Chondromyxoid Fibroma of Sphenoid Sinus with Unusual Calcifications: Case Report with Literature Review

“…Some authors have described a female predisposition for intracranial tumors [16, 17]. In the series of 33 cases reported by Karkuzhali et al [18], the most common site was in the frontal bones, followed by the sphenoid bone, occipital bones, temporal bones and clivus. The patients were predominantly in their fifth decade of life.…”

“…Calcifications may be noted either radiographically—in 3–16% of cases [3, 20]—or microscopically—in 7–27% of cases [3, 18, 20, 21]. Yamaguchi and Dorfman [22] have reported that patients with calcifications tend to be older (mean age 46 years) than those without calcifications (21 years), and that calcifications are associated with a longer duration of symptoms (43.2 months) compared to tumors without calcification (6.4 months).…”

Chondromyxoid fibroma in the sella turcica region

“…Karkuzhali ature, none of which were in the sellar region. 9 Location in the ethmoid, mastoid, clivus, temporal, occipital and spheno-occipital bones has been described. The symptoms of CMF include discomfort and pain accompanied by local swelling depending on the site and size of the tumor.…”

“…The CT scan shows osteolytic lesions with a sclerotic margin. 9 The tumor may show foci of calcification, with mineralization that is observed radiologically in about 13% of patients. 12 A low-to-intermediate signal intensity is observed on T1-weighted MRI and hyperintensity that indicates water content on T2-weighted MRI.…”

Soft tissue chondromyxoid fibroma of the foot: Sonographic findings

“…1 It also frequently affects flat bones. 5,6 Its typical radiographic finding manifests as a well-circumscribed, eccentric, osteolytic lesion with a sclerotic rim. 1 Histologically, chondromyxoid fibromas show stellate or spindle-shaped cells dispersed in the myxochondroid matrix, which has increased cellularity in the periphery dividing the matrix into pseudolobules.…”