Chondromyxoid fibroma affecting the maxilla in a 1-year-old child: Immunohistochemical analysis and literature review

Panucci, Beatriz Zamboni Martins; Silva, Evânio Vilela; Arévalo, Rafael Humberto Artero; Miranda, Ricardo Ernesto Rivera; Zelaya, Florence Juana María Cuadra; Silveira, Heitor Albergoni

doi:10.1016/j.oraloncology.2021.105467

Cited by 2 publications

(2 citation statements)

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“…Radiographic findings show well-defined tumors with sclerotic rims and scalloped margins; intra-tumor calcification; low signal intensity on T1-weighted images and heterogeneous high signal intensity on T2-weighted images [ 16 ]. In the respect of immunohistochemistry, a positive expression of CD10, which can help in the diagnostic process [ 17 ] (Fig. 6 B).…”

Section: Discussionmentioning

confidence: 99%

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Extraskeletal myxoid chondrosarcoma of the gingival: a rare case report and review of the literature

Li,

Zheng,

Deng

et al. 2023

Diagn Pathol

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Background Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant tumor described in the head and neck region, especially in the gingival. We present one case arising in the gingival of right mandible, and briefly reviewed the related literature. Case presentation A 24-year-old male patient with a lesion of 3.5*2.0 cm in buccal gingival of right posterior mandible for 2 months. The tumor was composed of cartilaginous structures and myxoid matrix. Immunohistochemical(IHC) showed that the tumor cells to be positive for vimentin, focally positive for S-100, negative for calponin, SMA, SOX10. The Ki-67 labelling index was 80%. Fluorescent in situ Hybridization (FISH) was positive for NR4A3 rearrangement. Conclusions Due to its unusual site and low incidence in the oral region, a combination of histological findings, immunohistochemistry, and molecular pathology as well as differential diagnosis with other diseases should be taken into consideration in the process of clinical diagnosis and treatment.

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Section: Discussionmentioning

confidence: 99%

“…6 A (HE × 40): Lobules of uniform spindle or stellate cells with myxoid or chondroid to fibrous stroma of CMF. B (IHC × 200): CD10, positive [ 17 , 18 ] …”

Section: Discussionmentioning

confidence: 99%