Chondroid tumors of the larynx: A clinicopathologic study of 19 cases, including two dedifferentiated chondrosarcomas

Casiraghi, Odile; Martı́nez-Madrigal, Fernando; Pineda‐Daboin, Keyla; Mamelle, G; Resta, L.; Luna, Mario A.

doi:10.1053/j.anndiagpath.2004.04.001

Cited by 74 publications

(87 citation statements)

References 15 publications

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“…Representan menos del 1% del total de los tumores laríngeos, y el 0,12% de todos los tumores de cabeza y cuello 4 . Se clasifican en 4 tipos: condrometaplasia, condroma, condrosarcoma y material cartilaginoso en otras neoplasias.…”

Section: Discussionunclassified

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Tumor condroide del cartílago tiroides: Reporte de un caso clínico y revisión de la literatura

Napolitano

et al. 2017

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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Section: Discussionunclassified

“…mujeres [4][5][6]8 . Con respecto a la edad, se han descrito casos desde el día 56 de vida, y hasta los 81 años 6 , con un máximo de incidencia variable, pero con una tendencia entre la sexta y séptima décadas de la vida 9 .…”

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Tumor condroide del cartílago tiroides: Reporte de un caso clínico y revisión de la literatura

Napolitano

et al. 2017

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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“…A variably dense, expansile lesion with characteristic ''popcorn'' calcifications is usually seen [1,4,7]. Invasion into adjacent soft tissue or bone E. M. Potochny (&) Á A. R. Huber Naval Medical Center San Diego, San Diego, CA, USA e-mail: evelyn.potochny@med.navy.mil may be present [1,3,4].…”

Section: Discussionmentioning

confidence: 99%

“…Since the majority of lesions are low-grade, the distinction from benign chondromas must be made. Chondromas are overall hypocellular, with predominantly small, mononucleated chondrocytes that retain normal N:C ratios and show no hyperchromasia, mitotic activity, or necrosis and may reside in an eosinophilic background matrix [1,[3][4][5]7]. Grade 1 chondrosarcomas demonstrate bi-or multinucleated chondrocytes with areas of calcification but which still lack mitotic activity.…”

Section: Discussionmentioning

confidence: 99%

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Laryngeal Chondrosarcoma

Potochny

Huber

2013

Head and Neck Pathol

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Laryngeal chondrosarcoma is a rare tumor requiring clinical, histologic, and radiographic correlation for definitive diagnosis. Although it typically presents with low-grade histology, even high-grade histology has a fairly indolent progression in this location, with a relatively low-likelihood for metastatic potential or recurrence. Because of this, conservative surgical excision with negative margins is recommended. We present a case of a laryngeal chondrosarcoma arising from the cricoid cartilage in a patient who presented with hoarseness, dysphagia, and odynophagia with subsequent head and neck computed tomography scan suggestive of the diagnosis. The patient was treated with hemicricoidectomy.

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Primary chondrosarcomas of the larynx treated with proton radiotherapy: A single institutional experience

et al. 2022

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Background Primary laryngeal chondrosarcomas are rare entities whose excellent survival rates following resection promote conservative surgical approaches to maintain quality of life without compromising outcomes. There are excellent outcomes in skull base chondrosarcomas treated with maximal safe resection and post‐operative proton therapy. Extrapolating from these findings, we report our institutional experience treating symptomatic or growing laryngeal chondrosarcomas using proton beam therapy. Cases Demographic information, clinical characteristics, treatment details, and follow‐up data were collected and summarized. Patients were monitored with serial imaging and examination. Stable disease was defined as no progression of disease on imaging. Two patients underwent subtotal resections followed by post‐operative radiotherapy, while two patients received definitive radiotherapy. All patients are currently alive with stable disease at their last follow‐up. Conclusion This case series provides initial evidence for excellent outcomes with maximal safe surgical resection followed by proton beam therapy for patients with symptomatic or growing laryngeal chondrosarcomas. Larger studies are warranted to determine the optimal therapeutic approach.

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Chondroid tumors of the larynx: A clinicopathologic study of 19 cases, including two dedifferentiated chondrosarcomas

Cited by 74 publications

References 15 publications

Tumor condroide del cartílago tiroides: Reporte de un caso clínico y revisión de la literatura

Tumor condroide del cartílago tiroides: Reporte de un caso clínico y revisión de la literatura

Laryngeal Chondrosarcoma

Primary chondrosarcomas of the larynx treated with proton radiotherapy: A single institutional experience

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