Cholinergic regulation of transcription processes in the liver

Dolgo-Saburov, V. B.; Podosinovikova, N. P.; Matveev, V. I.

doi:10.1007/bf00799264

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1981

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“…In previous studies we investigated the change in the activity of cholinesterases in certain tissues and organs of rabbits during postnatal ontogenesis [I], as well as in the subcellular fractions of the cerebral hemispheres of the developing animals' brains [2] and determined the basic kinetic parameters of acetylcholinesterase (ACHE) of the brain during the postembryonic period [i].…”

Section: Introductionmentioning

confidence: 99%

Study of the structuro-catalytic peculiarities of brain acetylcholinesterase in the postnatal ontogenesis of rabbits

Podosinovikova

Dolgo-Saburov

1981

Neurosci Behav Physiol

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The structuro-catalytic peculiarities of acetylcholinesterase (AChE) of the cerebral hemisphere of newborn, month-old, and adult rabbits were investigated. In the process of individual development, no changes were detected in the structure of the active surface of the enzyme, but differences were detected in the macromolecular organization and sensitivity to allosteric ligands. A hypothesis was advanced on the complication of the structural organization of AChE during postnatal ontogenesis. providing the possibility of the finest regulation of its activity.

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Section: Introductionmentioning

confidence: 99%