Cholesterotic fibrous histiocytoma with no associated dyslipidemia

Nakajima, Koji; Jin, Kayo; Kaneko, Takahide; Matsuzaki, Yasushi; Aizu, Takayuki; Nakano, Hajime; Sawamura, Daisuke

doi:10.1111/ijd.12380

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2021

2022

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Cited by 2 publications

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“…Although the patient did not have serologic evidence of dyslipidemia, it was thought that his antiretroviral medications, many of which are known to cause dyslipidemia, may have been a contributing factor to the development of cholesterol clefts. A more recent report from Spain 4 described one case in a 29‐year‐old female with no history of either hyperlipidemia or HIV infection.…”

Section: Discussionmentioning

confidence: 99%

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Cholesterotic fibrous histiocytoma: Case report and literature review

2021

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Cholesterotic fibrous histiocytoma is a particularly rare variant of dermatofibroma that is distinguished histopathologically by the presence of prominent cholesterol deposits within the lesion. We report the case of a 54‐year‐old male with poorly controlled hyperlipidemia who presented with a firm violaceous papule on the right shin, diagnosed as a cholesterotic fibrous histiocytoma. We also review and summarize the existing literature on this uncommon entity.

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Section: Discussionmentioning

confidence: 99%

“…Recognition of this entity by the pathologist is important, as it may represent a cutaneous expression of clinically significant hyperlipidemia. To our knowledge, there are only six previously reported cases of this entity 1‐6 …”

Section: Introductionmentioning

confidence: 99%