Cholesterol Point-of-Care Testing for Community Pharmacies: A Review of the Current Literature

Haggerty, Lauren C.; Tran, Deanna

doi:10.1177/0897190016645023

Cited by 23 publications

(21 citation statements)

References 24 publications

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“…The device used in the present study for the analysis of cholesterol levels has shown good accuracy compared to other brands and models. Since dyslipidemia is a risk factor for cardiovascular disease, it is recommended to screen populations; thus, the use of fingertip devices appears to be an appropriate alternative 15 .…”

Section: Discussionmentioning

confidence: 99%

The sensitivity, specificity, and agreement of a point of care method: an assessment of the diagnostic accuracy

Maciel

Quaresma

Figueiredo

et al. 2019

Ciênc. saúde coletiva

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The use of new technologies can improve screening in communities with difficult access to health. This article aims to evaluate the sensitivity, specificity, and agreement of a point of care test in comparison to laboratory methods for the determination of glucose (GLI), triglyceride (TG), and total cholesterol (TC) concentrations. This prospective study used data from the remaining adult population of quilombolas in Brazil. Laboratory tests using conventional methods for the analysis of venipuncture samples were used as a standard method to measure the concentrations of GLI (mg/dL), TG (mg/dL), and TC (mg/dL) and compared to the metered dose from the collection of fingertip capillary blood (point of care). Contingency tables (2x2) were used to estimate the sensitivity and specificity of the methods. Lin and Bland & Altman coefficients were used to statistically assess agreement, the level of significance was 5%. There was substantial agreement between the methods for measuring TG and poor agreement for of TC and GLI. Analysis of the Bland & Altman coefficients revealed that the fingertip method did not produce good measures. The point of care method did not offer a good ability to measure compared to that of the reference laboratory method.

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Section: Discussionmentioning

confidence: 99%

The sensitivity, specificity, and agreement of a point of care method: an assessment of the diagnostic accuracy

Maciel

Quaresma

Figueiredo

et al. 2019

Ciênc. saúde coletiva

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“…We used a smartphone-based, easy-to-use, intuitive user interface ( Figure 2) [12,13]. Smartphone-based point-of-care blood tests have several advantages in terms of computation, communication, usability, and cost-effectiveness [14,15]. In addition, data generated from point-of-care devices can be easily shared with caregivers and healthcare professionals, helping to manage chronic disease in patients.…”

Section: Discussionmentioning

confidence: 99%

Smartphone-Based Point-of-Care Cholesterol Blood Test Performance Evaluation Compared with a Clinical Diagnostic Laboratory Method

et al. 2019

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Featured Application: Faster, more convenient point-of-care cholesterol blood test.Abstract: Managing blood cholesterol levels is important for the treatment and prevention of diabetes, cardiovascular disease, and obesity. An easy-to-use, portable cholesterol blood test could accelerate more frequent testing by patients and at-risk populations. We aim to evaluate the performance of smartphone-based point-of-care cholesterol blood tests compared to that of hospital-grade laboratory tests. We used smartphone systems that are already familiar to many people. Because smartphone systems can be carried around everywhere, blood can be measured easily and frequently. We compared the results of cholesterol tests with those of existing clinical diagnostic laboratory methods. We found that smartphone-based point-of-care lipid blood tests were as accurate as hospital-grade laboratory tests (N = 116, R > 0.97, p < 0.001 for all three cholesterol blood tests, i.e., total cholesterol, high density lipoprotein, and triglyceride). Our system could be useful for those who need to manage blood cholesterol levels to motivate them to track and control their behavior.

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“…Pharmacists’ experience with other POC tests may inform their use of POC PGx testing and anticipated problems. A recent review of pharmacists’ use of POC testing for cholesterol found a positive impact on screening and identifying patients for referral for dyslipidemia [125]. In a health system, a pharmacist-operated anticoagulation clinic demonstrated reduced hospitalizations and increased time within the therapeutic range with a POC intervention [126].…”

Section: Challenges In Implementing Poc Pgx Testingmentioning

confidence: 99%

“…For example, POC creatinine testing can be administered by the pharmacist to patients with unknown renal status impairment; consultation with the physician can lead to changes in medication dosing and improved outcomes [127]. Reimbursement for POC testing will likely remain a major issue for pharmacists, regardless of test type [125,128]. Since state pharmacy boards define the scope of practice for pharmacists, a published review of pharmacy regulations reported that fewer than 20 percent of states addressed POC [129].…”

Section: Challenges In Implementing Poc Pgx Testingmentioning

confidence: 99%

Challenges of development and implementation of point of care pharmacogenetic testing

Haga

2016

Expert Review of Molecular Diagnostics

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This commentary will provide an overview of implementation research of PGx testing, the benefits of point-of-care (POC) testing and overview of POC testing platforms, available PGx tests, and barriers and facilitators to the development and integration of POC-PGx testing into clinical settings. Sources include the published literature, and databases from the Centers for Medicaid and Medicare Services, Food and Drug Administration. Expert commentary: The utilization of POC PGx testing may enable more routine test use, but the development and implementation of such tests will face some barriers before personalized medicine is available to every patient. In particular, provider training, availability of clinical decision supports, and connectivity will be key areas to facilitate routine use.

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Cholesterol Point-of-Care Testing for Community Pharmacies: A Review of the Current Literature

Cited by 23 publications

References 24 publications

The sensitivity, specificity, and agreement of a point of care method: an assessment of the diagnostic accuracy

The sensitivity, specificity, and agreement of a point of care method: an assessment of the diagnostic accuracy

Smartphone-Based Point-of-Care Cholesterol Blood Test Performance Evaluation Compared with a Clinical Diagnostic Laboratory Method

Challenges of development and implementation of point of care pharmacogenetic testing

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