volume 29, issue 2, P283-292 2012
DOI: 10.3233/jad-2011-111415
View full text
|
|
Share

Abstract: One of the hallmarks of Alzheimer’s Disease is a significant increase in ventricular volume. To date we and others have shown that a cholesterol-fed rabbit model of Alzheimer’s Disease displays as many as fourteen different pathological markers of Alzheimer’s Disease including amyloid β accumulation, thioflavin-S staining, blood brain barrier breach, microglia activation, cerebrovasculature changes and alterations in learning and memory. Using structural magnetic resonance imaging at 3T we now report that cho…

Expand abstract