Cholesterol Embolism in a Patient with Inflammatory Abdominal Aortic Aneurysm.

Suzuki, Yoshihiko; Kato, Jun; Kyoraku, Yuka; Nakamura, Kunihide; Onitsuka, Toshio; Kataoka, Hiroaki; Koono, Masashi; Eto, Tanenao

doi:10.2169/internalmedicine.38.861

Cited by 5 publications

(1 citation statement)

References 9 publications

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“…1 Among them, cholesterol crystal embolism has a poor prognosis and often might be fatal. 2 Endovascular aneurysm repair also has the potential of such risk in patients with severe atherosclerosis. 3 Supraceliac aorta or visceral artery clamping or balloon occlusion methods are usually used in this situation.…”

Section: Discussionmentioning

confidence: 99%

Débridement of atheroma in the proximal clamp site under hypothermic circulatory arrest for repair of abdominal aortic aneurysm with severe atherosclerosis

Yamauchi

Kubota

Hasegawa

2017

Journal of Vascular Surgery Cases, Innovations and Techniques

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Section: Discussionmentioning

confidence: 99%

Débridement of atheroma in the proximal clamp site under hypothermic circulatory arrest for repair of abdominal aortic aneurysm with severe atherosclerosis

Yamauchi

Kubota

Hasegawa

2017

Journal of Vascular Surgery Cases, Innovations and Techniques

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Érythème lombaire livédoïde révélateur d’un anévrisme thrombosé de l’aorte abdominale

Guérin

Avenel‐Audran

Pajot

et al. 2010

Annales de Dermatologie et de Vénéréologie

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Cholesterol Embolization Syndrome Induced by Thrombolytic Therapy

Hitti

Wali

Weinman

et al. 2008

American Journal of Cardiovascular Drugs

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Cholesterol embolization syndrome (CES) induced by thrombolytic therapy is a rare syndrome with a high incidence of morbidity and mortality. The variability in clinical presentations may cause a delay in diagnosis of CES. This article presents a comprehensive review of the English literature from January 1980 to December 2007 identifying all published case reports of CES induced by thrombolytic therapy. Multiple electronic databases were searched and relevant reference lists were hand searched to identify all case reports. Thirty cases of thrombolytic-induced CES were identified. Indications for thrombolysis were acute myocardial infarction (28 patients) and deep venous thrombosis (two patients). Skin and renal involvement were the most common presentations. Skin manifestations included livedo reticularis, rash, and skin mottling. Other clinical symptoms included cyanotic toes, gastrointestinal bleeding, or perforation, myalgias, retinal emboli, and CNS involvement. Morbidity and mortality were high. Outcomes included chronic hemodialysis in eight patients, four patients underwent amputations, seven patients developed or had progression of their chronic kidney disease, and seven deaths occurred.CES presents as multiorgan dysfunction and should be considered in the differential diagnosis of the symptom complex that may develop after thrombolytic therapy. Diagnosis of CES can be difficult as a result of the variable clinical presentations. A thorough clinical history and physical examination are essential first steps in establishing a diagnosis. Confirmatory diagnosis requires biopsy of the target organs. Measures to reduce the likelihood of recurrence should be taken and include avoidance of anticoagulation therapy and vascular procedures. Unfortunately, therapy remains supportive and the outcome is invariably poor.

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Cholesterol Embolism in a Patient with Inflammatory Abdominal Aortic Aneurysm.

Cited by 5 publications

References 9 publications

Débridement of atheroma in the proximal clamp site under hypothermic circulatory arrest for repair of abdominal aortic aneurysm with severe atherosclerosis

Débridement of atheroma in the proximal clamp site under hypothermic circulatory arrest for repair of abdominal aortic aneurysm with severe atherosclerosis

Érythème lombaire livédoïde révélateur d’un anévrisme thrombosé de l’aorte abdominale

Cholesterol Embolization Syndrome Induced by Thrombolytic Therapy

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