Cholesterol and Vitamin D and the Risk of Hyperemesis Gravidarum: A Mendelian Randomization Study
Xiaohu Liu,
Xiaoting Zhou,
Jiao Wang
et al.
Abstract:Background
Hyperemesis Gravidarum (HG) is becoming an increasingly substantial societal burden which affects 0.3–10.8% of pregnant women. Observational studies have investigated the impact of cholesterol and vitamin D on HG. However, the causality of associations among vitamin D, cholesterol and HG remains unknown.
Methods
We employed Bidirectional Mendelian randomization (MR) analysis and Multivariable MR (MVMR) to investigate the causal associations between cholesterol, vitamin D and HG. The causality was … Show more
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