Choledochal cyst with ectopic distal location of the papilla of Vater

Kim, Sung Kang; Jeong, Young Beom; Kim, Jae-Chun

doi:10.4174/jkss.2011.81.suppl1.s85

Cited by 2 publications

(1 citation statement)

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“…found that 67.8% (82/121) of children with CC who underwent ERCP had a distal opening of the major papilla to the descending duodenum [ 22 ]. Additionally, two studies reported that some patients with HDP were complicated by APBJ [ 23 , 24 ]. At present, the mechanism underlying the association between HDP and congenital abnormalities of the pancreaticobiliary duct remains unclear.…”

Section: Discussionmentioning

confidence: 99%

Horizontal duodenal papilla is associated with a special spectrum of pancreaticobiliary diseases: a retrospective magnetic resonance cholangiopancreatography-based study

Zhang,

Shi,

et al. 2023

Gastroenterology Report

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Background Horizontal duodenal papilla (HDP) is not an uncommon ectopic major papilla. The impact of HDP on the occurrence of pancreaticobiliary diseases remains unclear. Here, we explored the associations in patients who underwent magnetic resonance cholangiopancreatography (MRCP). Methods Consecutive patients who underwent MRCP at Xijing Hospital (Xi’an, China) between January 2020 and December 2021 were eligible. Patients were divided into HDP and regular papilla (RP) according to the position of the major papilla. The primary outcome was the proportion of congenital pancreaticobiliary diseases. Results A total of 2,194 patients were included, of whom 72 (3.3%) had HDP. Compared with the RP group (n = 2,122), the HDP group had a higher proportion of congenital pancreaticobiliary diseases, especially choledochal cyst (CC) or anomalous pancreaticobiliary junction (APBJ) (6.9% vs 1.4%, P = 0.001). More gallbladder cancer (6.9% vs 1.2%, P < 0.001) and pancreatic cysts (27.8% vs 16.3%, P = 0.01) were also identified in the HDP group. Morphologically, the HDP group had a longer extrahepatic bile duct (8.4 [7.6–9.3] cm vs 7.2 [6.5–8.1] cm, P < 0.001), and larger angles between the common bile duct-duodenum and pancreatic duct-duodenum. Multivariate analysis showed that the presence of HDP was an independent risk factor for gallbladder cancer. Conclusions This study confirmed that HDP was not rare in patients underwent MRCP. A higher prevalence of congenital pancreaticobiliary malformations (especially CC or APBJ), gallbladder cancer and pancreatic cysts was observed in patients with HDP, as well as distinctive morphologic features.

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Section: Discussionmentioning

confidence: 99%