Cholecystectomy - When and Why?

Sośnik, H; Sośnik, Katarzyna; Noga, Leszek

doi:10.2478/v10035-007-0101-z

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…Mucus surface also features nonglycosylated hydrophobic alternating regions containing cysteine residues. Nanoscale particle bulk or surface chemistry can be tailored to adhere to either or all of these moieties on the mucus surface via electrostatic and van der Waals forces and disulfide bridges [ 180–182 ] Table 6 exemplifies a number of natural and synthetic polymer nanoparticles developed for various mucoadhesive applications ranging from nasal mucus tissue to bladder mucus.…”

Section: Mucoadhesive Nanoparticlesmentioning

confidence: 99%

Recent Advances in Mucoadhesive Interface Materials, Mucoadhesion Characterization, and Technologies

Bayer

2022

Adv Materials Inter

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Mucoadhesion is an extremely important field of adhesion science and the comprehensive understanding and modulation of mucoadhesion can lead to lifesaving materials and technologies. For instance, deadly cases of COVID‐19 (SARS‐CoV‐2) cytokine storm are associated with viral adhesion and overproduction of mucus, which obstructs the airways. Mucin is the key polymeric compound that is known as a family of high molecular weight, heavily glycosylated proteins in epithelial tissues. Mucoadhesion can occur in many different ways such as receptor specific and charge interactions, covalent or noncovalent bonds. New mucin‐mimic polymers that replicate its beneficial traits can prevent biofilm formation and biofouling not only in biotechnology but also in membrane technologies. This review addresses the latest understandings related to mucin's role in wet adhesion considering different physiological conditions and shows how this translates into interfacial polymer adhesion. Advances in mucoadhesion measurement techniques including the rheological aspects of polymer–mucin adhesive interactions are presented. Specific mucoadhesive systems are discussed such as hydrogel mucoadhesion, catechol/dopamine functionalization, and polymeric nanoparticles. This overview may expand the current understanding of mucoadhesion between soft materials but also contributes to elastocapillary phenomena in soft materials design and applications such as new membranes, drugs, pharmaceutical devices, and lubricated surfaces.

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Section: Mucoadhesive Nanoparticlesmentioning

confidence: 99%

Recent Advances in Mucoadhesive Interface Materials, Mucoadhesion Characterization, and Technologies

Bayer

2022

Adv Materials Inter

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“…Así, estos materiales se utilizan ampliamente como matrices "inteligentes" para el suministro de fármacos y como andamios de ingeniería de tejidos que pueden ser inyectados por téc-nicas mínimamente invasivas [196]. Para polimerizar N-isopropilacrilamida, Shi y Liu emplearon PEG de peso molecular 600 g/mol como solvente, agente absorbente de la radiación y porógeno [197].…”

Section: Producción De Hidrogelesunclassified

Aplicaciones de la tecnología de radiación de microondas en la síntesis de biomateriales

Sosnik¹,

Gotelli²

Biomateriais Aplicados Ao Desenvolvimento De Sistemas Terapêuticos Avançados

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A navegação consulta e descarregamento dos títulos inseridos nas Bibliotecas Digitais UC Digitalis, UC Pombalina e UC Impactum, pressupõem a aceitação plena e sem reservas dos Termos e Condições de Uso destas Bibliotecas Digitais, disponíveis em https://digitalis.uc.pt/pt-pt/termos.Conforme exposto nos referidos Termos e Condições de Uso, o descarregamento de títulos de acesso restrito requer uma licença válida de autorização devendo o utilizador aceder ao(s) documento(s) a partir de um endereço de IP da instituição detentora da supramencionada licença.Ao utilizador é apenas permitido o descarregamento para uso pessoal, pelo que o emprego do(s) título(s) descarregado(s) para outro fim, designadamente comercial, carece de autorização do respetivo autor ou editor da obra. Na medida em que todas as obras da UC Digitalis se encontram protegidas pelo Código do Direito de Autor e Direitos Conexos e demais legislação aplicável, toda a cópia, parcial ou total, deste documento, nos casos em que é legalmente admitida, deverá conter ou fazer-se acompanhar por este aviso.Aplicaciones de la tecnología de radiación de microondas en la síntesis de biomateriales. Autor(es):Sosnik, Alejandro; Gotelli, Gustavo Resumen:El escalado industrial de la producción de biomateriales poliméricos sintéticos y semi-sintéticos enfrenta desafíos relevantes como la limitada reproducibilidad y difícil estandarización de los procesos sintéticos. más recientemente, a su implementación en la síntesis de polímeros y materiales cerámicos para aplicaciones terapéuticas. El presente capí-tulo presenta el Estado-del-Arte de las aplicaciones más destacadas de esta tecnología en la síntesis de biomateriales poliméricos orgánicos e inorgánicos y discute el potencial de la misma para optimizar la transferencia a la clínica de nuevos biomateriales.Palabras clave: Síntesis de biomateriales poliméricos asistida por radiación de microondas; polimerización de apertura de anillo;polimerización de injerto molecular; hidrogeles; micropartículas y nanopartículas; materiales compuestos. Abstract:The industrial scale-up of the production of synthetic and semisynthetic polymeric biomaterials faces challenges due to the limited reproducibility and difficult standardization of the synthetic methods.The scale-up demands the adjustment of the process variables, a phase that is crucial and that is associated with the growth of the produc- This chapter presents a State-of-the-Art of the most relevant applications of microwave radiation for the synthesis of organic and inorganic polymeric biomaterials and discusses its potential to optimize the bench-to-bedside translation of new biomaterials.

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Cholecystectomy - When and Why?

Cited by 2 publications

References 24 publications

Recent Advances in Mucoadhesive Interface Materials, Mucoadhesion Characterization, and Technologies

Recent Advances in Mucoadhesive Interface Materials, Mucoadhesion Characterization, and Technologies

Aplicaciones de la tecnología de radiación de microondas en la síntesis de biomateriales

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