Cholecystectomy Reduces Recurrent Pancreatitis and Improves Survival After Endoscopic Sphincterotomy

Young, Shih‐Hao; Peng, Yuting; Lin, Xi-Hsuan; Chen, Yung‐Tai; Luo, Jiing‐Chyuan; Wang, Yen‐Po; Hou, Ming‐Chih; Lee, Fa-Yauh

doi:10.1007/s11605-016-3284-y

Cited by 6 publications

(3 citation statements)

References 23 publications

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“…Taken together, the results of previous retrospective and prospective studies showed equivocal outcomes of recommendations for cholecystectomy [1][2][3][4][5][6][7][8][9][10][11]43]. However, several large-scale population-based studies and meta-analyses recommend cholecystectomy [28,31,32,36,37].…”

Section: Decision Of Prophylactic Cholecystectomy In the Real Worldmentioning

confidence: 95%

“…The HR for all-cause mortality among the cholecystectomy cohort was 0.75 (95% CI = 0.59-0.95; p = 0.016) compared with the control cohort. The authors concluded that prophylactic cholecystectomy should be recommended in these elderly patients [36]. Furthermore, in a population-based study of patients over 65 years of age, prophylactic cholecystectomy was significantly associated with a 50-70% RR reduction in recurrent CBD stones, cholangitis, and gallstone pancreatitis compared to only ES.…”

Section: Patients With Gb Stonesmentioning

confidence: 98%

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Prophylactic Cholecystectomy in Patients with Concomitant Gallstones After Removal of CBD Stones by ERCP

Park

2020

Diseases of the Gallbladder

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Section: Decision Of Prophylactic Cholecystectomy In the Real Worldmentioning

confidence: 95%

Section: Patients With Gb Stonesmentioning

confidence: 98%

Prophylactic Cholecystectomy in Patients with Concomitant Gallstones After Removal of CBD Stones by ERCP

Park

2020

Diseases of the Gallbladder

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“…Following Cotton's pioneering description of cannulation of the common bile duct (CBD) and McCune's first successful ERCP in the mid-1970's, ERCP has been widely adopted as the index therapeutic modality for clearance of CBD stones [4][5][6] and is most commonly performed either prior to or after operative removal of the gallstone reservoir at laparoscopic cholecystectomy. There have been variable approaches to sphincterotomy during ERCP with some preferring balloon dilation and others sphincterotomy [7][8][9]. Increasingly, ERCP is performed intra-operatively with a rendezvous technique with favourable outcomes reported [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Prophylactic cholecystectomy offers best outcomes following ERCP clearance of common bile duct stones: a meta-analysis

McGeehan

Melly²,

O'Connor³

et al. 2022

Eur J Trauma Emerg Surg

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Background Symptomatic calculus biliary disease is common with associated morbidity and occasional mortality, further confounded when there is concomitant common bile duct (CBD) stones. Choledocholithiasis and clearance of the duct reduces recurrent cholangitis, but the question is whether after clearance of the CBD if there is a need to perform a cholecystectomy. This meta-analysis evaluated outcomes in patients undergoing ERCP with or without sphincterotomy to determine if cholecystectomy post-ERCP clearance offers optimal outcomes over a wait-and-see approach. Methods A Prospero registered meta-analysis of the literature using PRISMA guidelines incorporating articles related to ERCP, choledocholithiasis, cholangitis and cholecystectomy was undertaken for papers published between 1st January 1991 and 31st May 2021. Existing research that demonstrates outcomes of ERCP with no cholecystectomy versus ERCP and cholecystectomy was reviewed to determine the related key events, complications and mortality of leaving the gallbladder in situ and removing it. Odds ratios (OR) were calculated using Review Manager Version 5.4 and meta-analyses performed using OR using fixed-effect (or random-effect) models, depending on the heterogeneity of studies. Results 13 studies (n = 2598), published between 2002 and 2019, were included in this meta-analysis, 6 retrospective, 2 propensity score-matched retrospective studies, 3 prospective studies and 2 randomised control trials from a total of 11 countries. There were 1433 in the no cholecystectomy cohort (55.2%) and 1165 in the prophylactic cholecystectomy (44.8%) cohort. Cholecystectomy resulted in a decreased risk of cholecystitis (OR = 0.15; CI 0.07–0.36; p < 0.0001), cholangitis (OR = 0.51; CI 0.26–1.00; p = 0.05) and mortality (OR = 0.38; CI 0.16–0.9; p = 0.03). In addition, prophylactic cholecystectomy resulted in a significant reduction in biliary events, biliary pain and pancreatitis. Conclusions In patients undergoing CBD clearance, consideration should be given to performing prophylactic cholecystectomy to optimise outcomes.

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Biliary Intervention in Acute Gallstone Pancreatitis

Korman¹,

Carr‐Locke²

2019

Ercp

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Cholecystectomy Reduces Recurrent Pancreatitis and Improves Survival After Endoscopic Sphincterotomy

Abstract: Cholecystectomy decreased the subsequent recurrent acute pancreatitis and the all-cause mortality in elderly patients with EST and clearance of BD stones after gallstone-related acute pancreatitis.

Cited by 6 publications

References 23 publications

Prophylactic Cholecystectomy in Patients with Concomitant Gallstones After Removal of CBD Stones by ERCP

Prophylactic Cholecystectomy in Patients with Concomitant Gallstones After Removal of CBD Stones by ERCP

Prophylactic cholecystectomy offers best outcomes following ERCP clearance of common bile duct stones: a meta-analysis

Biliary Intervention in Acute Gallstone Pancreatitis

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