Cholangitis after the Kasai operation for biliary atresia

Prophylactic Antibiotics for Prevention of Cholangitis in Patients With Biliary Atresia Status Post-Kasai Portoenterostomy

“…[8][9][10] Despite overall improvements in both postoperative management and short-term BA outcomes, the incidence of cholangitis has changed very little. One of the most common of these complications is postoperative cholangitis, which affects more than 50% of patients.…”

Conditional probability of survival in patients with biliary atresia after Kasai portoenterostomy: a Chinese population-based study

“…Cholangitis was a serious complication after hepatic portoenterostomy in patients with BA. It had an estimated incidence between 40% and 80% of patients and usually developed in the first year after operation [34,35]. Cholangitis was considered one of the most important determinants of long-term survival after a successful hepatic portoenterostomy [36,37].…”

Late-presenting cholangitis and Roux loop obstruction after Kasai portoenterostomy for biliary atresia

“…However, in the absence of a specific test for the diagnosis of cholangitis, blood cultures being positive only in 10% to 50% and liver cultures in about 30% [4,18], then deterioration of biochemical liver function and an accompanying pyrexial illness must be minimum criteria for accurate diagnosis.…”

“…There have been a number of methods reported with the aim of diminishing the incidence of recurrent cholangitis. These have included pharmacological intervention, such as long-term antibiotic prophylaxis [21,22] and corticosteroid bblastQ therapy [18], and surgical techniques, such as Roux loop stomas [23,24], Roux loop lengthening, and mucosal intussusception valves [25,26]. Although all have generated a degree of enthusiasm in their initiators, the experience in larger series has been unconvincing and none has really gained widespread acceptance [6,27].…”