CHOICE OF MANAGEMENT METHOD OF MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH LOW LEFT VENTRICULAR EJECTION FRACTION (&lt;35 %): A RANDOMIZED PROSPECTIVE STUDY

Николаев, Д. А.; Бобошко, А. В.; Boboshko, Vladimir; Чернявский, А. М.; Kornilov, Igor; Шилова, А. Н.; Ломиворотов, В. Н.; Ломиворотов, В. В.

doi:10.17802/2306-1278-2016-3-21-34

Kompleks. probl. serdečno-sosud. zabol.

2016

DOI: 10.17802/2306-1278-2016-3-21-34

|View full text |Cite

CHOICE OF MANAGEMENT METHOD OF MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH LOW LEFT VENTRICULAR EJECTION FRACTION (<35 %): A RANDOMIZED PROSPECTIVE STUDY

Д. А. Николаев¹,

А. В. Бобошко²,

Vladimir Boboshko³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

References 20 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Levosimendan: current and possible areas of clinical application: A review

Boboshko,

Zibareva,

Lomivorotov

2023

Annals of Critical Care

Self Cite

View full text Add to dashboard Cite

Levosimendan belongs to the class of calcium sensitizers, which exhibits its positive inotropic effects by increasing the affinity of troponin from the myocardium to calcium without additional myocardial oxygen demand, what favorably distinguishes it from catecholamines and their negative effects (myocardial ischemia, arrhythmias, vasoconstriction, hyperglycemia). In 2000, the drug was first used for the short-term treatment of decompensated chronic heart failure. After more than 20 years, the clinical use of levosimendan has covered a wide area among patients with pathology of the cardiovascular system and its use has gone far beyond the primary indications. To date, the drug has been studied in more than 200 randomized trials in patients with various clinical profiles: acute decompensation of chronic heart failure, progressive heart failure, acute myocardial infarction, cardiogenic shock, therapy of low cardiac output syndrome in cardiac surgery, perioperative use in pediatric cardiac surgery, septic shock, pulmonary hypertension, right ventricular failure, Takotsubo cardiomyopathy, patients with mechanical circulatory support devices. This review highlights the pharmacological features of the drug and key randomized clinical trials on the use of levosimendan in various categories of patients, in addition to officially recommended indications. The article also provides a brief overview of current and planned randomized trials.

show abstract

Levosimendan: current and possible areas of clinical application: A review

Boboshko,

Zibareva,

Lomivorotov

2023

Annals of Critical Care

Self Cite

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

CHOICE OF MANAGEMENT METHOD OF MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH LOW LEFT VENTRICULAR EJECTION FRACTION (<35 %): A RANDOMIZED PROSPECTIVE STUDY

Cited by 1 publication

References 20 publications

Levosimendan: current and possible areas of clinical application: A review

Levosimendan: current and possible areas of clinical application: A review

Contact Info

Product

Resources

About