Chocolate in Health and Nutrition 2012
DOI: 10.1007/978-1-61779-803-0_32
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Chocolate and Pain Tolerance

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“…In fact, labor was associated with activation of nuclear factor-kappa B and will be increased the prostaglandin ( 22 ). Endogenous opioids cause a euphoric mood and lower pain sensitivity by interacting with neurotransmitter systems ( 9 ), creating an analgesic effect to decline the pain. Another possible mechanism of dark chocolate reduced the labor pain, may be the mechanism of polyphenols' antioxidant and cortisol-lowering actions, have been proposed.…”
Section: Discussionmentioning
confidence: 99%
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“…In fact, labor was associated with activation of nuclear factor-kappa B and will be increased the prostaglandin ( 22 ). Endogenous opioids cause a euphoric mood and lower pain sensitivity by interacting with neurotransmitter systems ( 9 ), creating an analgesic effect to decline the pain. Another possible mechanism of dark chocolate reduced the labor pain, may be the mechanism of polyphenols' antioxidant and cortisol-lowering actions, have been proposed.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, a chocolate intervention rich in polyphenols decreased salivary cortisol levels, which is known to modulate the hypothalamic-pituitary-adrenal (HPA) axis ( 24 ). Given that the HPA axis is involved in pain and stress-related disorders ( 9 , 24 ), the reduction in cortisol and polyphenols' antioxidant caused by chocolate consumption may contribute to the pain-regulating effects of cocoa.…”
Section: Discussionmentioning
confidence: 99%
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