Chlorosulfonylated calix[4]arenes: precursors for neutral anion receptors with a selectivity for hydrogen sulfate

A phenylhydrazone-based indole receptor for sensing acetate

“…So, the design of anion receptors with high selectivity is challenging [9][10][11]. Synthetic receptors for anions are usually based on urea/thiourea [12,13], amides [14,15,25], macrocyclic ammonium/guanidinium [16,17], functionalized calixarenes [18,19], phenylhydrazone [20], indole [21] and -OH [26]. Take the phenylhydrazone for example, first, this kind of the receptor is neutral and the synthetic method is simple.…”

A NovelN-linked Peptidocalix[4]arene Receptor for Anions

“…Among them there are a few examples of fluoroionophores based on peptidocalixarenes developed for anion recognition. Previously, we reported two cone calix [4]arene conformers which exhibited good recognition to F 2 and AcO 2 , respectively [28,29]. In this paper, we report another anion chemosensor based on a Nlinked peptidocalix [4]arene which showed selective fluorescent behavior of F 2 over other anions examined such as Cl 2 , Br 2 , I 2 , HSO 2 4 , NO 2 3 , AcO 2 and H 2 PO 2 4 .…”

Simple Calix[n]arenes and Calix[4]resorcinarenes as Drug Solubilizing Agents

“…They must be functionalized with suitable groups in order to make them soluble and relevant for studies in drug solubilization. Shinkai et al first reported the synthesis of water-soluble calix[n]arenes bearing sulfonate functional groups on the upper rim and alkyloxy groups on the lower rim [32][33][34][35]. The interior cavity of calix[n]arenes and calix [4]resorcinarenes in the cone conformation is typically hydrophobic and this can be exploited to form reversible host-guest complexes with small organic molecules via non-covalent interactions.…”