“…Nowadays, chloroquine and hydroxychloroquine are used to treat autoimmune and connective tissue diseases like systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjögren's syndrome, sarcoidosis, palindromic rheumatism, eosinophilic fasciitis, dermatomyositis, cellulitis, mixed and undifferentiated connective tissue disease (11,13,14). They have also demonstrated anticancer properties against different types of cancer (e.g., colon, lung and breast cancer, central nervous system tumors, hematological malignancies), and against cancer cell lines in vitro (11,15). CQ has also demonstrated antiviral activity, and has been used in clinical trials in infections caused by hepatitis C virus, dengue virus-2, human immunodeficiency virus, and Chikungunya virus (15).…”