“…The effect of chloramphenicol on typhoid fever has been described thus (Cook and Marmion, 1949): “Clinically speaking, the effect … seems to be to arrest the disease at whatever stage it has reached, and to sterilize the blood at the same time; defervescence takes place within five days, and convalescence then starts. In consequence a patient treated fairly early in his illness is spared much of the drawn‐out fever and toxaemia associated with the classical picture of typhoid.” The contrast is illustrated by Figs.…”