Encyclopedia of Life Sciences 2020
DOI: 10.1002/9780470015902.a0000039.pub3
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Chloride Channels

Abstract: Chloride channels are integral membrane proteins that regulate the movement of chloride ions across cellular membranes. They perform a vital role in physiological processes such as epithelial transport, the regulation of nerve and muscle cell membrane excitability, cell volume regulation and in determining the pH within cytoplasmic membrane‐bound organelles. Several distinct protein families form chloride channels whose opening is regulated by different stimuli including neurotransmitter binding, changes in th… Show more

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