Chlorhexidine urticaria: A rare occurrence with a common mouthwash

Sharma, Anamika; Chopra, Harneet

doi:10.4103/0970-9290.57368

Cited by 26 publications

(4 citation statements)

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“…Due to a significant rise in bacterial strains resistant to antibiotics, it has become necessary to explore herbal medications and their antibacterial properties that help to improve the results of biomechanical preparations. 20 Endodontic irrigants may be made from a variety of plant extracts that have antibacterial, anti-inflammatory, and therapeutic properties. The following are some of the most significant herbal irrigants: neem , tulsi, aloe vera, ACV, Morinda citrifolia (M. citrifolia) , and Curcuma longa .…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study

Gupta,

Singh,

Sudhakar

et al. 2023

International Journal of Clinical Pediatric Dentistry

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A bstract Aim The purpose of the study is to compare and evaluate the efficacy of different root canal irrigants—100, 75, 50, and 25% neem extract, 100, 75, 50, and 25% apple cider vinegar (ACV), a combination of 5.25% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA), and saline on smear layer removal using a scanning electron microscope (SEM). Materials and methods A total of 80 freshly extracted single-rooted teeth were collected and divided into 10 groups—group I: normal saline (negative control), group II: NaOCl with EDTA (positive control), group III: 100% neem extract, group IV: 75% neem extract, group V: 50% neem extract, group VI: 25% neem extract, group VII: 100% ACV, group VIII: 75% ACV, group IX: 50% ACV, and group X: 25% ACV. The samples were irrigated with a specific group of irrigants, then split in a longitudinal axis and processed for analysis in an SEM. Microphotographs were obtained and scored according to Torabinejad et al. Results Microphotographs were assessed and showed that 100% neem extract was similar to NaOCl with EDTA, followed by 75% neem extract and 100% ACV. Conclusion This study showed that 100% neem extract removed the smear layer, similar to the NaOCl with EDTA. How to cite this article Sudhakar S, Gupta N, Ghambir N, et al. Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study. Int J Clin Pediatr Dent 2023;16(4):633–638.

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Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study

Gupta,

Singh,

Sudhakar

et al. 2023

International Journal of Clinical Pediatric Dentistry

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“…The adverse effects of chlorhexidine are reported as altered taste sensation, superficial desquamation of the oral mucosa, brownish discoloration of the tongue and teeth, increased calculus formation and stomach upsets ( 42 ). Rare reports are published about cutaneuos adverse reactions following the use of CHL in mouth-wash rinses resembling fixed drug eruption or contact stomatitis, urticaria and anaphylaxis are reported after the use of CHL mouth-wash rinses ( 34 , 35 , 43 , 44 , 45 , 46 ). The patients in many reported cases later tested positive for chlorhexidine induced hypersensitivity reaction by means of intradermal, scratch, and epicutaneous tests ( 43 , 45 , 47 , 48 ).…”

Section: Introductionmentioning

confidence: 99%

Potential Hazards Due to Food Additives in Oral Hygiene Products

Budanur¹,

Yaş²,

Sepet³

2016

J Istanbul Univ Fac Dent

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Food additives used to preserve flavor or to enhance the taste and appearance of foods are also available in oral hygiene products. The aim of this review is to provide information concerning food additives in oral hygiene products and their adverse effects. A great many of food additives in oral hygiene products are potential allergens and they may lead to allergic reactions such as urticaria, contact dermatitis, rhinitis, and angioedema. Dental practitioners, as well as health care providers, must be aware of the possibility of allergic reactions due to food additives in oral hygiene products. Proper dosage levels, delivery vehicles, frequency, potential benefits, and adverse effects of oral health products should be explained completely to the patients. There is a necessity to raise the awareness among dental professionals on this subject and to develop a data gathering system for possible adverse reactions.

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“…However, CHG does not affect spore-forming bacteria and viruses without envelopes. In addition, although CHG has been reported to induce contact dermatitis, the incidence of this condition is very low 14 , 15 .…”

Section: Introductionmentioning

confidence: 99%

“…A number of studies have investigated the effects of these different antiseptic agents in subjects with normal skin conditions 7 - 9 , 14 , 16 . However, the effect of hand disinfectants containing these antiseptic agents on AD remains unclear.…”

Section: Introductionmentioning

confidence: 99%

Effect of the Hand Antiseptic Agents Benzalkonium Chloride, Povidone-Iodine, Ethanol, and Chlorhexidine Gluconate on Atopic Dermatitis in NC/Nga Mice

Sadakane¹,

Ichinose²

2015

Int. J. Med. Sci.

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Antiseptic agents can cause skin irritation and lead to severe problems, especially for individuals with atopic diatheses. We investigated the effect of 4 different antiseptic agents using an atopic dermatitis (AD) model mouse. NC/Nga mice were subcutaneously injected with mite allergen (Dp) to induce AD-like skin lesions (ADSLs), and an application of 0.2% (w/v) benzalkonium chloride (BZK), 10% (w/v) povidone-iodine (PVP-I), 80% (v/v) ethanol (Et-OH), or 0.5% (v/v) chlorhexidine gluconate (CHG) was applied to the ear envelope. BZK induced a significant increase in the severity of the clinical score, infiltration of inflammatory cells, local expression of inflammatory cytokines in subcutaneous tissue, and total serum immunoglobulin (Ig) E. PVP-I increased the clinical score, number of mast cells, and production of inflammatory cytokines, and total serum IgE. Et-OH increased the clinical score and number of inflammatory cells, but showed no effect on serum IgE levels. No differences in any parameters were observed between CHG and the vehicle. Collectively, the results suggest the severity of the ADSL was related in part to the strength of the immunoreaction. These findings suggest that CHG could offer the lowest risk of inducing ADSL in individuals with atopic dermatitis and that medical staff and food handlers with AD could benefit from its use.

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Chlorhexidine urticaria: A rare occurrence with a common mouthwash

Cited by 26 publications

References 0 publications

Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study

Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study

Potential Hazards Due to Food Additives in Oral Hygiene Products

Effect of the Hand Antiseptic Agents Benzalkonium Chloride, Povidone-Iodine, Ethanol, and Chlorhexidine Gluconate on Atopic Dermatitis in NC/Nga Mice

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