Chlordane as undesirable substance in animal feed - Scientific Opinion of the Panel on Contaminants in the Food Chain

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doi:10.2903/j.efsa.2007.582

Cited by 5 publications

(2 citation statements)

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“…Its PTDI is 500 ng kg −1 b.w. per day, based on liver toxicity in rats [ 45 ]. The calculated EDI of chlordane is 0.012 ng kg −1 b.w.…”

Section: Resultsmentioning

confidence: 99%

“…The active principle is commonly p-p’ DDT, but also the metabolites op’ DTT, and the isomers of DDT and DDE are found in the mixture named “DDT complex.” The JMPR [ 50 ] reviewed several studies that could also include some metabolites other than pp’ DDT. IARC classifies DDT in Group 2A (probably carcinogenic to humans) based on sufficient evidence in experimental animals, but limited evidence in humans, that DDT exposure can cause non-Hodgkin lymphoma, testicular cancer, and liver cancer [ 45 ]. Based on studies of developmental toxicity in rats as the endpoint, the PTDI of DTT complex was estimated as 1 × 104 ng kg −1 b.w.…”

Section: Resultsmentioning

confidence: 99%

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Organohalogenated Substances and Polycyclic Aromatic Hydrocarbons in Fish from Mediterranean Sea and North Italian Lakes: Related Risk for the Italian Consumers

Mosconi

Cesare

Arioli

et al. 2022

Foods

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The primary source of persistent organic pollutant (POP) exposure is food, especially fish. European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata) are among the most eaten sea fish in Italy. Fish from lakes in Northern Italy, such as agone (Alosa agone), represent niche consumption for most people, but possibly constitute a much larger percentage of overall consumption volume for local residents. This study dealt with the presence of POPs in the above-mentioned fish species via GC-MS/MS analysis. None of the analytes for which maximum limits are in place showed concentrations above those limits. Moreover, none of the substances without maximum limits exceeded the provisional tolerable daily intake (PTDI) when given, nor did they exceed the more general values considered safe, even for 99th percentile consumers.

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“…Its PTDI is 500 ng kg −1 b.w. per day, based on liver toxicity in rats [ 45 ]. The calculated EDI of chlordane is 0.012 ng kg −1 b.w.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%