Chitosan resistance by the deletion of the putative high affinity glucose transporter in the yeast Ustilago maydis

Olicón-Hernández, Darío Rafael; Araiza-Villanueva, Minerva Georgina; Vázquez-Carrada, Melissa; Guerra-Sánchez, Guadalupe

doi:10.1016/j.carres.2021.108335

Cited by 1 publication

(1 citation statement)

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“…It is worth mentioning that in-depth studies into the interactions between chitosan and fungal cell membranes are scarce. Intriguingly, the absence of a putative glucose transporter in U. maydis resulted in resistance against chitosan [ 53 ]. Moreover, inhibiting ergosterol biosynthesis acts as a vital way for chitosan to disturb plasma membrane integrity, which is one of the most important components of fungal cell membranes [ 54 ], and the fact that ergosterol is a prominent site of action for chitosan is accepted as a plausible opinion, which represents the important correlation between chitosan and fungal cell membranes [ 55 ].…”

Section: Advances In Rational Construction Of Chitosan-based Nano-the...mentioning

confidence: 99%

Functional Chitosan and Its Derivative-Related Drug Delivery Systems for Nano-Therapy: Recent Advances

Wang,

Yu,

2024

Pharmaceutics

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In the struggle against diseases, the development of nano-therapy has certainly been a tremendous progression owing to the various superiority, and chitosan is no doubt a kind of prominent biopolymer material with versatility for applications in disease treatments. For the rational construction of chitosan-related nano-biodevices, it is necessary to pay full attention to the material itself, where it is the material properties that guide the design criteria. Additionally, the well-matched preparation methods between material carriers and therapeutic agents draw much attention to the final construction since they seem to be more realistic. In detail, we present a comprehensive overview of recent advances in rational construction of chitosan-related nano-therapies with respect to material-property-oriented design criteria and preparation methods in the current review article, based on the foundation of continuous investigations. Based on this review, a portion of the various uses of chitosan-related nano-biodevices for biomedical applications are specifically discussed. Here, the strategies demonstrate the versatility of chitosan well, and the concept of being simple yet effective is well illustrated and vividly communicated. Altogether, a fresh concept concerning multi-functional chitosan and its derivative-related drug delivery systems for nano-therapy is proposed in this review, and this could be applied to other materials, which seems to be a novel angle.

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Section: Advances In Rational Construction Of Chitosan-based Nano-the...mentioning

confidence: 99%

Functional Chitosan and Its Derivative-Related Drug Delivery Systems for Nano-Therapy: Recent Advances

Wang,

Yu,

2024

Pharmaceutics

View full text Add to dashboard Cite

show abstract

Chitosan resistance by the deletion of the putative high affinity glucose transporter in the yeast Ustilago maydis

Cited by 1 publication

References 30 publications

Functional Chitosan and Its Derivative-Related Drug Delivery Systems for Nano-Therapy: Recent Advances

Functional Chitosan and Its Derivative-Related Drug Delivery Systems for Nano-Therapy: Recent Advances

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