Chitosan/Polyvinylpyrrolidone/MCM‐41 Composite Hydrogel Films: Structural, Thermal, Surface, and Antibacterial Properties

Abstract

The aim of this study is to characterize and investigate the effects of the Mobil Composition of Matter No. 41 (MCM-41) concentrations (0.5, 1, 3, 5, and 10 wt%) on structural, thermal, wettability, water content, oxygen (O 2 ) permeability, and swelling properties as well as morphological characteristics of chitosan/polyvinylpyrrolidone/MCM-41 (CH/PVP/MCM-41) composite hydrogel films. In addition, hydrolytic degradability, optic transmittance, and antibacterial properties of composite hydrogels films are determined as in vitro. With increasing of MCM-41 content, the composite hydrogels showed higher thermal stability, as expected. The morphologic properties of the composite hydrogel films are studied using scanning electron microscope (SEM) technique that provide evidence for good miscibility of CH, PVP, and MCM-41. The swelling and water-absorbing properties of the composite hydrogel films are significantly improved because of enhanced hydrophilic profile. Furthermore, the antimicrobial properties of the prepared composite hydrogel films are studied against Bacillus subtilis, Escherichia coli, and Candida albicans yeast. The results showed excellent antibacterial behavior of the composite hydrogel films. The study clearly demonstrates that the prepared CH/PVP/MCM-41 composite hydrogel films may be used as a promising candidate material in various fields such as drug delivery, wound healing material, and adsorbent materials.

Recent Developments of Nanomaterials in Hydrogels: Characteristics, Influences, and Applications

“…Carbon nanotubes (CNT) are embedded in chitosan hydrogel beads as nanofillers, and the thermal stability and chemical resistance of the hydrogel are improved due to the good interfacial interaction between them and the chitosan matrix [70] . CH/PVP/MCM‐41 composite hydrogel, the molecular interaction between the amino group of CH and silanol (Si), the MCM‐41 group can improve thermal stability [113] . The strong interaction between the nanomaterial and the polymer substrate reduces the mobility of the polymer side chain, and the graphitized structure in the matrix system can act as a thermal barrier, which greatly improves the thermal stability of the hydrogel [71] .…”

“…[70] CH/PVP/ MCM-41 composite hydrogel, the molecular interaction between the amino group of CH and silanol (Si), the MCM-41 group can improve thermal stability. [113] The strong interaction between the nanomaterial and the polymer substrate reduces the mobility of the polymer side chain, and the graphitized structure in the matrix system can act as a thermal barrier, which greatly improves the thermal stability of the hydrogel. [71] The thermal stability of the nanocomposite hydrogel can also be improved by increasing the water content.…”

Chemistry, Structures, and Advanced Applications of Nanocomposites from Biorenewable Resources

“…The most important common features expected in nanocomposites made from biorenewable resources are biocompatibility, biodegradability, easy preparation, low density, low cost, and suitability for modifications . Besides these commonly seen features, low thermal conductivity, increased flexibility, low dielectric constant, and good workability depending on the application are also general properties of these structures. , However, the lower thermal, mechanical, and chemical stability compared to structures originating from petroleum has restricted their industrial applicability in many applications.…”

Biodegradable Dual-Function Nanocomposite Hydrogels for Prevention of Bisphosphonate-Related Osteonecrosis of the Jaw

“…The combinations of polymeric biomaterials and MSNs for drug delivery applications have attracted great attention. − Recently, we have successfully developed the CDM-loaded composite hydrogels consisting of biodegradable CMCS and CDM-loaded unmodified or plasma-treated MCM-41 nanoparticles . The composite hydrogels with prolonged release profiles of up to 10 days effectively inhibited the growth of Streptococcus sanguinis for at least 14 days in vitro .…”