Chitosan–Polyvinyl Alcohol Nanocomposites for Regenerative Therapy

Abstract

Tissue accidents provide numerous pathways for pathogens to invade and flourish, causing additional harm to the host tissue while impeding its natural healing and regeneration. Essential oils (EOs) exhibit rapid and effective antimicrobial properties without promoting bacterial resistance. Clove oils (CEO) demonstrate robust antimicrobial activity against different pathogens. Chitosan (CS) is a natural, partially deacetylated polyamine widely recognized for its vast antimicrobial capacity. In this study, we present the synthesis of four membrane formulations utilizing CS, polyvinyl alcohol (PVA), and glycerol (Gly) incorporated with CEO and nanobioglass (n-BGs) for applications in subdermal tissue regeneration. Our analysis of the membranes’ thermal stability and chemical composition provided strong evidence for successfully blending polymers with the entrapment of the essential oil. The incorporation of the CEO in the composite was evidenced by the increase in the intensity of the band of C-O-C in the FTIR; furthermore, the increase in diffraction peaks, as well as the broadening, provide evidence that the introduction of CEO perturbed the crystal structure. The morphological examination conducted using scanning electron microscopy (SEM) revealed that the incorporation of CEO resulted in smooth surfaces, in contrast to the porous morphologies observed with the n-BGs. A histological examination of the implanted membranes demonstrated their biocompatibility and biodegradability, particularly after a 60-day implantation period. The degradation process of more extensive membranes involved connective tissue composed of type III collagen fibers, blood vessels, and inflammatory cells, which supported the reabsorption of the composite membranes, evidencing the material’s biocompatibility.

Bryophyte-Bioinspired Nanoporous AAO/C/MgO Composite for Enhanced CO2 Capture: The Role of MgO

“…Therefore, the high density of pores observed in bryophytes may serve as a critical morphological feature for CO 2 adsorption, as it enhances the physical accessibility of CO 2 molecules to the active sites involved in the capture process. The FTIR spectrum is shown in Figure 1 d, where the band at 989 cm −1 is attributed to cellulose C-O stretching, the band at 1013 cm −1 to pectin groups, the band at 1126 cm −1 to polysaccharides, and the band at 3321 cm −1 to cellulose O-H bending [ 32 , 33 , 34 , 35 ]. This suggests a significant presence of organic molecules in the sample as expected.…”