Chitosan films and scaffolds for regenerative medicine applications: A review

Rezaei, Farnoush Sadat; Sharifianjazi, Fariborz; Esmaeilkhanian, Amirhossein; Salehi, Ehsan

doi:10.1016/j.carbpol.2021.118631

Cited by 92 publications

(53 citation statements)

References 172 publications

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“…In this survey, ZnO nanoparticles were encapsulated with chitosan to improve the stability of the nanomaterial led to its cationic charge and hydrophilicity properties [113]. Another major aspect of the application of nanoparticles is their use as a means of gene transfer to various cells, especially tumor cells [82,114]. There are several benefits to the application of this system for gene transfer.…”

Section: Drug Deliverymentioning

confidence: 99%

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Sol-gel zinc oxide nanoparticles: advances in synthesis and applications

et al. 2021

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Zinc oxide nanoparticles (ZnO) exhibit numerous characteristics such as biocompatibility, UV protection, antibacterial activity, high thermal conductivity, binding energy, and high refractive index that make them ideal candidates to be applied in a variety of products like solar cells, rubber, cosmetics, as well as medical and pharmaceutical products. Different strategies for ZnO nanoparticles’ preparation have been applied: sol-gel method, co-precipitation method, etc. The sol-gel method is an economic and efficient chemical technique for nanoparticle (NPs) generation that has the ability to adjust the structural and optical features of the NPs. Nanostructures are generated from an aqueous solution including metallic precursors, chemicals for modifying pH using either a gel or a sol as a yield. Among the various approaches, the sol-gel technique was revealed to be one of the desirable techniques for the synthesis of ZnO nanoparticles. In this review, we explain some novel investigations about the synthesis of zinc oxide nanoparticles via sol-gel technique and applications of sol-gel zinc oxide nanoparticles. Furthermore, we study recent sol-gel ZnO nanoparticles, their significant characteristics, and their applications in biomedical applications, antimicrobial packaging, drug delivery, semiconductors, biosensors, catalysts, photoelectron devices, and textiles.

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Section: Drug Deliverymentioning

confidence: 99%

“…Biosensors can diagnose various significant biological molecules with high accuracy and sensitivity [114,131,132]. Biosensors are mainly used for the detection of various diseases, cell imaging, measurement of nucleotide sequences, etc.…”

Section: Biosensormentioning

confidence: 99%

Sol-gel zinc oxide nanoparticles: advances in synthesis and applications

et al. 2021

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“…Conductive polymers have long been a popular choice for actuators among polymeric materials. Most research organizations have taken use of PEDOT: electroactive PSS's characteristics [43,98].…”

Section: Drug Deliverymentioning

confidence: 99%

An overview of materials, processing, and applications for wearable electronics

Eskandarinezhad

Yusuf

2021

jcc

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Wearable electronics are gaining widespread attention because of the potential applications of them in systems of wearable human care and health monitoring. These new devices are probably a collection of different applications like batteries, sensors, displays, and so on. In these respects, conductive fibers, inks, and fabrics were examined. On the field, three materials categories including carbon, metal, and polymer-based materials were investigated. Materials of carbon have advantages like good electrical conductivity, structural and inherent flexibility, high thermal and chemical stability, light weight, ease of chemical operation, and potential production of mass, enabling them to be a good candidate for wearable and flexible electronics. Conducting polymers have a number of drawbacks in their natural state; however, by combining them with other materials, these drawbacks can be solved. Conducting polymer composites have a wide range of applications in optoelectronic, electronic, and electrical sectors due to their synergetic effects. Liquid metal was bestowed with new-emerging characteristics and multifunctional applications. Due to the high surface tension and limited adherence on many surfaces, the manufacturing approach of patterning liquid metals on flexible substrates has received a lot of attention up to now.The current state of wearable materials as actuators and fabrication processes are discussed in this review paper.

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“…The employment of the chitosan scaffold alone is restricted by its poor mechanical and quick biodegradation characteristics. Still, when combined with a suitable modifier, it yields promising results by enhancing scaffold stability [8]. Thein-Han et al [9] developed biodegradable chitosan-nanohydroxyapatite (nHA) scaffolds with superior physicochemical, biological, and mechanical properties as compared to chitosan scaffolds alone.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites

et al. 2022

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Green bionanocomposites have garnered considerable attention and applications in the pharmaceutical and packaging industries because of their intrinsic features, such as biocompatibility and biodegradability. The work presents a novel approach towards the combined effect of glycerol, tween 80 and silver nanoparticles (AgNPs) on the physicochemical properties of lyophilized chitosan (CH) scaffolds produced via a green synthesis method.The produced bionanocomposites were characterized with the help of Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM). The swelling behavior, water vapor transmission rate, moisture retention capability, degradation in Hanks solution, biodegradability in soil, mechanical strength and electrochemical performance of the composites were evaluated. The addition of additives to the CH matrix alters the physicochemical and biological functioning of the matrix. Plasticized scaffolds showed an increase in swelling degree, water vapor transmission rate and degradability in Hank’s balanced solution compared to the blank chitosan scaffolds. The addition of tween 80 made the scaffolds more porous, and changes in physicochemical properties were observed. Green-synthesized AgNPs showed intensified antioxidant and antibacterial properties. Incorporating biogenic nanoparticles into the CH matrix enhances the polymer composites’ biochemical properties and increases the demand in the medical and biological sectors. These freeze-dried chitosan-AgNPs composite scaffolds had tremendous applications, especially in biomedical fields like wound dressing, tissue engineering, bone regeneration, etc.

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Chitosan films and scaffolds for regenerative medicine applications: A review

Cited by 92 publications

References 172 publications

Sol-gel zinc oxide nanoparticles: advances in synthesis and applications

Sol-gel zinc oxide nanoparticles: advances in synthesis and applications

An overview of materials, processing, and applications for wearable electronics

Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites

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