Chitosan-Coated Magnetic Nanoparticles Prepared in One Step by Reverse Microemulsion Precipitation

Abstract

Chitosan-coated magnetic nanoparticles (CMNP) were obtained at 70 °C and 80 °C in a one-step method, which comprises precipitation in reverse microemulsion in the presence of low chitosan concentration in the aqueous phase. X-ray diffractometry showed that CMNP obtained at both temperatures contain a mixture of magnetite and maghemite nanoparticles with ≈4.5 nm in average diameter, determined by electron microscopy, which suggests that precipitation temperature does not affect the particle size. The chitosan coating on nanoparticles was inferred from Fourier transform infrared spectrometry measurements; furthermore, the carbon concentration in the nanoparticles allowed an estimation of chitosan content in CMNP of 6%–7%. CMNP exhibit a superparamagnetic behavior with relatively high final magnetization values (≈49–53 emu/g) at 20 kOe and room temperature, probably due to a higher magnetite content in the mixture of magnetic nanoparticles. In addition, a slight direct effect of precipitation temperature on magnetization was identified, which was ascribed to a possible higher degree of nanoparticles crystallinity as temperature at which they are obtained increases. Tested for Pb2+ removal from a Pb(NO3)2 aqueous solution, CMNP showed a recovery efficacy of 100%, which makes them attractive for using in heavy metals ion removal from waste water.

Physicochemical Characterization and Biocompatibility of SPION@Plasmonic @Chitosan Core-Shell Nanocomposite Biosynthesized from Fungus Species

“…These bands have been assigned for the γFe 2 O 3 iron oxide phase [29]. The FTIR data is in agreement with the work done by López et al and Liang et al [10,30] interpreting the same peaks for the formation of chitosan coating layer around the core shell.…”

“…Silver has been used in ancient time as an effective antimicrobial agent in operations and utensils, and therefore has been widely introduced as antimicrobial and antifungal in industry. Recently, the silver nanoparticles have been applied for cancer treatment causing selective induction of apoptosis [9,10].…”

Synthesis of Poly(N-vinylcaprolactam)-Grafted Magnetite Nanocomposites for Magnetic Hyperthermia

“…From this figure, it can be seen that all samples show magnetic behavior close to superparamagnetic materials with low values of coercivity (Hc) and remanence (Mr). Also, it can be seen that the presence of VTMS and PNVCL in the MagNP surface decreases the saturation magnetization values (Ms) causing a diminution of the MagNP magnetic moments [17,18]. However, these values are in the range used for biomedical applications [19,20].…”

Magnetic drug delivery systems

“…Chitosan-coated MNPs contain a core of magnetic material, usually a mixture of Fe3O4 and γ-Fe2O3 [81], or hybrid MNPs (nickel-ferrite) [82], with the drug loaded on the surface for targeted, controlled release. Dorniani et al [83] designed a new drug nanocarrier by coating chitosan and perindopril erbumine on the surface of MNPs using a simple coating method.…”