Abstract:Numerous natural polymers either alone or in combination with other polymers were found effective in controlling the drug release. In this study the attempts were made to combine chitosan (degree of deacetylation 84.14 %) and as hydroxylpropyl methylcellulose (HPMC K 15M) to retard the release of aceclofenac in tablet formulation. The tablets were prepared by wet granulation and evaluated for pre and post- compression parameters. All the pre-compression parameters were found within the limit. Hardness and fri… Show more
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