2003
DOI: 10.1002/mabi.200300019
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Chitosan: An Attractive Biocompatible Polymer for Microencapsulation

Abstract: Chitosan is a weak cationic polysaccharide composed essentially of β(1 → 4) linked glucosamine units together with some N‐acetylglucosamine units. It is obtained by extensive deacetylation of chitin, a polysaccharide common in nature. Chitosan is a biocompatible, biodegradable, and nontoxic natural polymer that exhibits excellent film‐forming ability. As a result of its cationic character, chitosan is able to react with polyanions giving rise to polyelectrolyte complexes. Therefore, because of these interestin… Show more

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Cited by 239 publications
(122 citation statements)
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“…These coating materials are effective to protect bacteria from harsh environment such as acidic pH. The stirring rate, level of the gelling agent, temperature, concentration of the surfactant polymer and the viscosities of the phases were reported to influence morphology and size of particles (Peniche et al, 2003).…”
Section: Chitosanmentioning
confidence: 99%
“…These coating materials are effective to protect bacteria from harsh environment such as acidic pH. The stirring rate, level of the gelling agent, temperature, concentration of the surfactant polymer and the viscosities of the phases were reported to influence morphology and size of particles (Peniche et al, 2003).…”
Section: Chitosanmentioning
confidence: 99%
“…They can be drug carrier system such as liposomes. Other drug delivery systems are based on using nanoparticles composed of biodegradable polymers, this has been explained in the earlier subsection on polymeric drug delivery system [17]. These microparticles may consist of polymeric nanospheres in an oily reservoir or aqueous medium.…”
Section: Nanoparticle Delivery Systemsmentioning
confidence: 99%
“…It is a cationic linear polysaccharide composed of a deacetylated unit (β-(1-4)-linked glucosamine) and a acetylated unit (N-acetyl-D-glucosamine) in a random order. Chitosan does not occur in nature too oftenbecause of that, it is obtained by deacetylation of chitin (component of the cell walls of fungi and the exoskeletons of arthropods) [30]. The mentioned polysaccharide is nontoxic, biodegradable and biocompatible; all these features make it useful in medicine and pharmacy [31].…”
Section: Biopolymers Used In Microencapsulationmentioning
confidence: 99%