Chiral Separations by Capillary Electrophoresis and related Techniques with Different Chiral Selectors: A Review

Şarkaya, Koray; Göktürk, İlgım; Yılmaz, Fatma; Deni̇zli̇, Adil

doi:10.15671/hjbc.815414

Cited by 5 publications

(1 citation statement)

References 316 publications

(312 reference statements)

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“…the gel forming a layer of cations (Fig. 4) on the pore wall [37]. The bulk positive layer could move towards the cathode (negative electrode) and the negative ions could move towards the anode (positive electrode).…”

Section: Gel Electromembrane Extraction (G-eme)mentioning

confidence: 99%

Application of oxygen scavenger in gel electromembrane extraction for determination of nitrite and nitrate

Samkumpim

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Gel electromembrane microextraction (G-EME) have been proven as a promising extraction method due to its effectiveness for extraction and preconcentration of charged analytes and its compliance with the principle of green chemistry. G-EME consists of two phases (donor and acceptor phases), separated by a gel membrane made of agarose. The driving force is the electrical potential applied across the membrane. Despite of all the advantages, the common problem was the oxygen generated in the acceptor solution due to the electrolysis of water that could affect the analysis of easily oxidized analyte species such as nitrite/nitrate species. In this work, application of oxygen scavenger to the acceptor solution has been attempted and studied to prevent or minimize this effect in G-EME for determination of nitrite and nitrate ions. Several oxygen scavengers such as ascorbic acid, iron, sulfite, and bisulfite were tested and examined. Ion chromatography was used for quantitative analysis of nitrite and nitrate ions. The mixture of sulfite and bisulfite (14 ppm) in the acceptor solution could prevent the oxidation of nitrite to nitrate effectively. After optimizing all the parameters, the method was successfully applied for speciation of nitrite and nitrate in water samples giving the linear calibration curves in the range of 10 to 200 ?g L-1, the limits of detection were 12 ?g L-1 and 13 ?g L-1, respectively, for both nitrite and nitrate ions. This method was successfully applied to the simultaneous determination of nitrite and nitrate spiked into sausage and water samples at the sub-ppm range.

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Section: Gel Electromembrane Extraction (G-eme)mentioning

confidence: 99%

Application of oxygen scavenger in gel electromembrane extraction for determination of nitrite and nitrate

Samkumpim

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Chiral Separation by Capillary Electrophoresis and Capillary Electrophoresis–Mass Spectrometry

Clark¹,

Somsen²,

Köhler³

2023

Chiral Separations and Stereochemical Elucidation

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Enantiomeric Analysis of Chiral Drugs Using Mass Spectrometric Methods: A Comprehensive Review

Vallamkonda,

Sethi,

Satti

et al. 2024

Chirality

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Chirality plays a crucial role in the drug development process, influencing fundamental chemical and biochemical processes and significantly affecting our daily lives. This review provides a comprehensive examination of mass spectrometric (MS) methods for the enantiomeric analysis of chiral drugs. It thoroughly investigates MS‐hyphenated techniques, emphasizing their critical role in achieving enantioselective analysis. Furthermore, it delves into the intricate chiral recognition mechanisms inherent in MS, elucidating the fundamental principles that govern successful chiral separations. By critically assessing the obstacles and potential benefits associated with each MS‐based method, this review offers valuable insights for researchers navigating the complexities of chiral analysis. Both qualitative and quantitative approaches are explored, presenting a comparative analysis of their strengths and limitations. This review is aimed at significantly enhancing the understanding of chiral MS methods, serving as a crucial resource for researchers and practitioners engaged in enantioselective studies.

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Chiral Separations by Capillary Electrophoresis and related Techniques with Different Chiral Selectors: A Review

Cited by 5 publications

References 316 publications

Application of oxygen scavenger in gel electromembrane extraction for determination of nitrite and nitrate

Application of oxygen scavenger in gel electromembrane extraction for determination of nitrite and nitrate

Chiral Separation by Capillary Electrophoresis and Capillary Electrophoresis–Mass Spectrometry

Enantiomeric Analysis of Chiral Drugs Using Mass Spectrometric Methods: A Comprehensive Review

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