Chiral Oxazolidine Complexes Derived from Phenolic Schiff Bases

Abstract

Schiff bases derived from pyridyl-or salicyl-aldehydes and aminoalcohols can evolve to heterocyclic oxazolidines, which in the presence of cations allow the formation of uncommon coordination compounds. In this work, we report new Ni II and mixed valence Mn II / Mn IV complexes derived from pyridyl oxazolidines and the unprecedented characterization of enantiomerically pure oxazolidines derived from the condensation of o-vanillin with phenylglycinol in the presence of Ni II cations. The different reactivity of the pyridinic or phenolic Schiff bases has been compared, and the new systems have been structurally, optically, and magnetically characterized.

Synthesis, Spectroscopic Identification for Mixed-Ligand Complexes and Evaluating Their Biological Effectiveness

“…It was not surprising; therefore, that many authors have studied the coordination compounds of several central atoms. Mixed ligand complexes had a key role in biological chemistry (5) because the mixed chelation occurs commonly in biological fluids as millions of potential ligands were likely to compete for metal ions in-vivo (6) . These create specific structures (7) and have been implicated in the storage and transport of active substances through membranes.…”