Chiral inorganic nanomaterials for biological applications

Abstract

Chiral nanomaterials in biology play indispensable roles in maintaining numerous physiological processes, such as signaling, site-specific catalysis, transport, protection, and synthesis. Like natural chiral nanomaterials, chiral inorganic nanomaterials could also...

Modulation of the assembly fashion among metal–organic frameworks for enantioretentive epoxide activation

“…Specifically, basic building blocks like amino acids, saccharides and ribonucleic acids in life are all enantiopure chiral substances and rigorously comply with a specific set of chirality selection rules when performing their biological functionalities. [1][2][3] Thanks to vigorous advances of chiral science made in biomedicines, 4 pesticides, 5,6 fine chemicals, 7 chiroptics, 8 and so on, 9 the increasing demand for various types of chiral substances in high enantiopurity has been an urgent task in chiral synthesis and asymmetric catalysis. [10][11][12][13] For instance, the enantioretentive alcoholysis of epoxide substrates is an important way to synthesize chiral b-alkoxy alcohols with 1,2-disynthons introduced, which are multifunctional chiral intermediates irreplaceable in preparations of chiral polyurethane elastomers, anticancer eugenol b-amino alcohols and derivatives.…”

Organic chiral nano- and microfilaments: types, formation, and template applications

“…While researchers' attention focuses equally on inorganic [15][16][17] as well as organic building blocks to generate chiral nanofilaments, this review will focus exclusively on organic chiral nanofilaments. By discussing a select number of example systems, the aim is to (1) draw analogies in nanofilament formation among the most prevalent materials classes, (2) work out and compare common design principles, and (3) elucidate the underlying driving forces for chiral nanofilament formation.…”

Enhancement of Fluorescence Mediated by Silver Nanoparticles: Implications for Cell Imaging

“…A wide range of biomedical applications have been developed and commercially available with the advancement of fluorescence emission spectroscopic techniques, synthesis of a variety of new fluorescent compounds, as well as modern device sophistication. The synthesis of new organic and inorganic probe materials with unique physical and physicochemical properties has spurred the systematic investigation of protein localization and biological function of living cells. , Cellular imaging by the fluorescence technique is an excellent analytical approach that has revolutionized the molecular cell biology and related fields through the assessment or identification of the dynamical behavior of intra- or extracellular components of a variety of living cells in real time, i.e., by fluorescence imaging microscopy.…”