Chiral functionalization of solid surfaces with amino acid derivatives: diazonium grafting regulated by enantioselective processes

Abstract

Chiral inorganic nanostructures are essential for many enantioselective processes. It is possible to bestow chirality to otherwise achiral inorganic materials, via covalent functionalization of their surfaces with chiral organic molecules....

When ionic liquids meet diazonium salts to generate thin layers of modified surfaces

“…While obtaining dense and thin layers is possible through the optimization of experimental parameters (time / scan rate, concentration, potential), [23][24][25] more efficient strategies were reported over the last years to obtain monolayers. Namely, it could either be performed using sterically hindered ligands (protecting groups, calix [4]arenes), [9,26] redox inhibitors, [27] long alkyl chains, [28] enantioselective species, [29] or simply through ascorbic acid mediated dediazoniation. [30] Although countless methods have been developed to modify surfaces through diazonium chemistry and finely tune the geometry of the grafted layer, one should notice that all the investigations are performed in classical solvents (water and acetonitrile).…”