Chiral [(Dialkylamino)methyl](phospholyl)ferrocene Ligands as a New Class of 1,2‐Disubstituted Ferrocene Ligands

Abstract

An efficient synthesis of new chiral [(dialkylamino)methyl]-(phospholyl)ferrocenes in an enantiomerically pure form has been developed. These new chiral N,P ligands have been tested in the palladium-catalyzed allylic substitution reac-

Chiral and Extended π‐Conjugated Bis(2‐pyridyl)phospholes as Assembling N,P,N Pincers for Coordination‐Driven Synthesis of Supramolecular [2,2]Paracyclophane Analogues

“…[14] Given the versatility and popularity of phospholes in coordination chemistry, it is surprising that, despite their potential use in asymmetric catalysis, very few chiral phosphole ligands have been described to date. [13,15] A recent development that combines coordination chemistry and p-conjugated systems is the use of mixed pyridine-phosphole derivatives for coordination-driven supramolecular synthesis of complex architectures. For example, multidipolar NLOphore A [16] and metal-bisA C H T U N G T R E N N U N G (helicene) assembly B [17] were obtained by stereoselective coordination of predesigned p-conjugated P,N ligands to a Pd 2 + center ( Figure 1).…”

“…[5] The most important application of metal-phosphole complexes is in homogeneous catalysis. For example, they have been used in diverse catalytic processes such as olefin/CO copolymerization, [9] hydroformylation of olefins, [10] Suzuki-Myaura and Heck couplings, [11] telomerization reactions, [12] allylic alkylation, [13] and hydrogenation of ketones. [14] Given the versatility and popularity of phospholes in coordination chemistry, it is surprising that, despite their potential use in asymmetric catalysis, very few chiral phosphole ligands have been described to date.…”

FT-IR, NMR spectroscopic and quantum mechanical investigations of two ferrocene derivatives

“…Because of the redox potential of the ferrocene, different types of organic materials which contain ferrocene moiety were prepared and used in several applications [1][2][3][4][5][6][7]. On the other hand, some ligands and complexes including ferrocene moiety were prepared for the inorganic applications [8][9][10][11]. Ferrocenoyl amino acids and peptides were prepared using acyl ferrocenes and investigated in detail [12][13][14][15].…”

New Chiral Ferrocene‐Bridged Phosphole–Phosphane Ligands

“…[14k] 1-phenyldibenzophosphole [30] and compounds 3a, 4a, 5a and 6a [12] were prepared as described in the literature.…”

“…[12] Chiral phosphole-based ligands [13] have been rather infrequently used for asymmetric catalysis, [14] despite the fact that phospholes are efficient ligands in homogeneous transition-metal catalysis.…”