Chinese Herbal Products for Ischemic Stroke

Abstract

Traditional Chinese herbal products (CHPs) have been described in ancient medicine systems as treatments for various stroke-associated ailments. This study is aimed to investigate the prescription patterns and combinations of CHPs for ischemic stroke in Taiwan. Prescriptions of CHPs for ischemic stroke were obtained from the National Health Insurance Research Database (NHIRD) of Taiwan. Every prescription with a leading diagnosis of ischemic stroke made during 2000-2010 was analyzed. Descriptive statistics were applied to the pattern of co-prescriptions. Multiple logistic regression models were used to assess demographic and risk factors that are correlated with CHP use. The dataset of inpatient claims data contained information on 15,896 subjects who experienced ischemic stroke from 2000 to 2010. There was an average of 5.82 CHPs in a single prescription for subjects with ischemic stroke. Bu-yang-huan-wu-tang (BYHWT) (40.32%) was by far the most frequently prescribed formula CHP for ischemic stroke, and the most commonly used combination of two-formula-CHP was BYHWT with Shu-jin-huo-xue-tang (SJHXT) (4.40%). Dan Shen (16.50%) was the most commonly used single CHP for ischemic stroke, and the most commonly used combination of two single CHPs was Shi Chang Pua with Yuan Zhi (4.79%). We found that BYHWT and Dan Shen were the most frequently prescribed formula and single CHP for ischemic stroke, respectively. These results provide information about individualized therapy and may contribute to further pharmacologic experiments and clinical trials.

Complementary Therapy with Traditional Chinese Medicine for Ischemic Stroke

“…Dan Shen was the most commonly prescribed single CHP for ischemic stroke (16.50%), and Shi Chang Pua with Yuan Zhi was the most commonly prescribed single-CHP combination (4.79%). These results provide information about individualized stroke therapy and propose specific CHP components and formulas for further pharmacological investigation and clinical evaluation [16].…”

Analysis of the Medical Market Share of Traditional East Asian Medicine (TEAM) in Taiwan Using National Health Insurance Research Database (NHIRD)

“…Insomnia and depression In 2002∼2010, 37% of patients diagnosed with insomnia used hypnotic drug and herbal medicine in combination 53) In 2003, 42.73% of patients with major and mild depressive disorder who were prescribed antidepressant used TEAM 54) In 64,65) In 2008, The acupuncture utilization rate of stroke patients increased to 17% 66) In 2000, 24% of stroke patients used TEAM, but in 2009, they increased to 32% 67) In 2000∼2010, 77.30% of newly diagnosed ischemic stroke patients used TEAM 68) Atrial fibrillation In 2000∼2011, 15.35% of newly diagnosed atrial fibrillation patients used TEAM within 7 days 69) Heart failure In 2001∼2010, 78.50% of newly diagnosed heart failure patients used TEAM 70) Ischemic heart disease In 2000∼2010, 81.59% of newly diagnosed ischemic heart disease patients used TEAM 71) Diseases of the respiratory system (7.53%)…”

An Intersectional Study of LncRNAs and mRNAs Reveals the Potential Therapeutic Targets of Buyang Huanwu Decoction in Experimental Intracerebral Hemorrhage

“…Buyang Huanwu decoction (BYHWD) is the most frequently prescribed formula for stroke treatment (40.32%) [14]. Evidence-based investigations have found that BYHWD improves neurological deficiencies in both experimental studies and clinical trials [15-17].…”