Chinese Herbal Medicine for premature ovarian failure: A systematic review and meta-analysis

Wu, Yan; Chen, Luting; Qu, Fan; Sheikh, Irfan; Wu, Yanting

doi:10.1016/j.eujim.2014.01.008

Cited by 11 publications

(2 citation statements)

References 7 publications

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“…It showed that acupuncture treatment increased serum E2 (MD 31.51, 95% CI: 6.06–56.95, P = 0.02) levels and reduced serum FSH (MD −9.26, 95% CI: −13.11–−5.41, P < 0.00001) levels. These results are similar with Wu et al's [ 30 ] study: they reported that CHM might relieve symptoms of POI partly through increasing E2 levels (MD 22.00, 95% CI: 2.90–41.10, P = 0.024) and thereby decreasing serum FSH levels (MD −6.59, 95% CI: −9.06 to–−4.12, P < 0.001) in patients with POI. There were no significant differences in LH levels in both studies.…”

Section: Discussionsupporting

confidence: 93%

Effectiveness of Acupuncture for Primary Ovarian Insufficiency: A Systematic Review and Meta-Analysis

Lee

2015

Evidence-Based Complementary and Alternative Medicine

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Objective. This systematic review aimed to assess current evidence from randomized controlled trials (RCTs) on the effects of acupuncture for patients with primary ovarian insufficiency (POI). Methods. We searched twelve databases to identify relevant studies published before July 2014. The outcomes were serum follicle-stimulating hormone (FSH) levels and resumption of menstruation. Two reviewers independently assessed the risk of bias using the Cochrane's tool, extracted the results, and evaluated the overall level of the evidence using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. Results. Eight RCTs were selected. Acupuncture significantly lowered serum FSH levels and more women receiving acupuncture reported resumption of menses. However, the results should be interpreted with caution due to a small number of participants, high risk of bias for blinding, and likely publication bias. The level of evidence for FSH level and resumption of menses were assessed as “low” using GRADE. Conclusion. The current evidence on acupuncture for POI is insufficient to draw a firm conclusion due to scarcity of studies with a low risk of bias and likely publication bias. Further rigorously designed and conducted studies are needed to confirm the effectiveness and safety of acupuncture in patients with POI.

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Section: Discussionsupporting

confidence: 93%

Effectiveness of Acupuncture for Primary Ovarian Insufficiency: A Systematic Review and Meta-Analysis

Lee

2015

Evidence-Based Complementary and Alternative Medicine

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“…Conversely, in traditional Persian medicine, the etiology of amenorrhea is divided into uterus etiology including the obstruction or blockage in the uterus due to dystemperament or inflammations, and the like, as well as common etiologies such as occasional dystemperament in the body or any disease in other organs which may disrupt mensuration (15,20,21). Several studies were found to use traditional and herbal methods to treat early menopause (2,(22)(23)(24) The patient of the current study reported having cold and dry dystemperament (suolmizaj) based on traditional medicine rules, which caused complaints about vaginal dryness, dyspareunia, obsessions thoughts, parasomnia, nightmare, the darkness of skin color, and dryness and itching of the skin. Digestive disorders of the patient were due to cold and dry dystemperament in the stomach leading to dyspepsia through which the elements fail to be properly absorbed and therefore are unable to reach the other parts properly.…”

Section: Discussionmentioning

confidence: 84%

Management of Early Menopause Using Traditional Persian Medicine: A Case Report

Behnoud

Bahrami

Kordafshari

et al. 2018

International Journal of Women’s Health and Reproduction Scienc

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Interruption of the activity of ovary before the age of forty is called premature ovarian failure (POF) in which ovaries lose their follicular and hormonal functions. A decline in the number of ovules before the age of menopause is a physiologic phenomenon. In the present case report, treatment of a patient by POF was reported using traditional Persian medicine principles. In Persian medicine, each humor has its own temperament. A change in the temperament and quality or quantity of these humors causes the disease and therefore modifying the temperament is the milestone of treatment. The patient was a 39-year-old married woman with irregular menstruation cycles and finally, cessation of menstruation. In this period, the patient had vaginal dryness, severe dyspareunia, gastritis, and parasomnia. At first, some instructions were ordered to change her lifestyle, for example, a change in food intakes, enough sleep, and exercise. In addition, several medications were ordered including the digestive system electuary (Majoun Jahaz Hazemeh), Eyaraj Fighara capsule and powder containing Glycyrrhiza glabra roots, Foeniculum vulgare and white sugar, oil massage of the abdomen and flanks, and cupping of the uterus. At the end of treatment, complete rehabilitation was achieved and menstruation irregularity, gastritis, and parasomnia were resolved. Based on the results, if a patient follows the rules and has a healthy lifestyle, inappropriate humor is unable to appear, the healing can be stable, and this disease or similar melancholic disorders fail to occur

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A general description for Chinese medicine in treating premature ovarian failure

Lin

Song

et al. 2017

Chin. J. Integr. Med.

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Premature ovarian failure (POF) is a kind of gynecological disease that causes amenorrhea, infertility, menopause and urogenital symptoms. Currently hormone replacement therapy (HRT) is the most popular choice for women with POF to get rid of menopausal syndrome. However, as the popularization of Chinese herbs made Chinese medicine (CM) shine new lights, physicians are able to treat POF with both meno-herbs and integrated therapy. HRT has its own indications and contraindications. For example, unexplained vaginal bleeding, acute liver damage, liver dysfunction, vascular embolization, and breast cancer are all contraindications of HRT, and CM is taken by more physicians as an adjuvant therapy. This review, including a range of common Chinese herbs and formulations according to the existing literature, provides a general description of CM treating POF from the aspects of mechanisms and clinical application. It also highlights acupuncture as a unique physiotherapy for POF. Although the validity of CM has been supported by the evidence of many preclinical trials, clinical trials and meta-analysis, the adverse events with CM therapy still exist and no guarantee has been made for its safety. This review concludes the updated information for CM treating POF contributing to further studies.

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Chinese Herbal Medicine for premature ovarian failure: A systematic review and meta-analysis

Cited by 11 publications

References 7 publications

Effectiveness of Acupuncture for Primary Ovarian Insufficiency: A Systematic Review and Meta-Analysis

Effectiveness of Acupuncture for Primary Ovarian Insufficiency: A Systematic Review and Meta-Analysis

Management of Early Menopause Using Traditional Persian Medicine: A Case Report

A general description for Chinese medicine in treating premature ovarian failure

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